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2. Aminoshikimic acid - Wikipedia

   en.wikipedia.org/wiki/Aminoshikimic_acid

   Aminoshikimic acid is an intriguing alternative to shikimic acid as a starting material for the synthesis of neuraminidase inhibitors such as the antiinfluenza agent oseltamivir. [3] Aminoshikimic acid is also a versatile chiral starting material for the synthesis of new pharmaceuticals. As with shikimic acid, aminoshikimic acid is an ...

3. Shikimic acid - Wikipedia

   en.wikipedia.org/wiki/Shikimic_acid

   Although shikimic acid is present in most autotrophic organisms, it is a biosynthetic intermediate and in general found in very low concentrations. The low isolation yield of shikimic acid from the Chinese star anise is blamed for the 2005 shortage of oseltamivir. Shikimic acid can also be extracted from the seeds of the sweetgum (Liquidambar ...

4. Oseltamivir - Wikipedia

   en.wikipedia.org/wiki/Oseltamivir

   Oseltamivir was discovered by scientists at Gilead Sciences using shikimic acid as a starting point for synthesis; shikimic acid was originally available only as an extract of Chinese star anise; but by 2006, 30% of the supply was manufactured recombinantly in E. coli. [65] [66] Gilead exclusively licensed their relevant patents to Roche in ...

5. FDA Issues Urgent Warning on Dangers of Common Dog Medication

   www.aol.com/lifestyle/fda-issues-urgent-warning...

   The United States Food and Drugs Administration is warning pet owners about a common medication given to pets to treat arthritis. The F.D.A. now says that the drug Librela may be associated with ...

6. Popular dog arthritis medication Librela linked to pet ... - AOL

   www.aol.com/popular-dog-arthritis-medication...

   A popular arthritis medication for dogs has sickened thousands of pets and likely caused others to die, the Food and Drug Administration said in an urgent warning. Dangerous side effects from the ...

7. Illicium verum - Wikipedia

   en.wikipedia.org/wiki/Illicium_verum

   [10] [11] [12] An industrial method for the production of shikimic acid using fermentation of E. coli bacteria was discovered in 2005, [13] [14] and applied in the 2009 swine flu pandemic to address Tamiflu shortages, eventually reversing price increases for star anise as a raw material of shikimic acid. [15]