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  2. Mycophenolic acid - Wikipedia

    en.wikipedia.org/wiki/Mycophenolic_acid

    Although it is not commercialised as antibiotic due to its adverse effects, its modified compound (ester derivative) is an approved immunosuppressant drug in kidney, heart, and liver transplantations, and is marketed under the brands CellCept (mycophenolate mofetil by Roche) and Myfortic (mycophenolate sodium by Novartis). [45]

  3. Phases of clinical research - Wikipedia

    en.wikipedia.org/wiki/Phases_of_clinical_research

    This is continued until pre-calculated pharmacokinetic safety levels are reached, or intolerable side effects start showing up (at which point the drug is said to have reached the maximum tolerated dose (MTD)). If an additional unacceptable toxicity is observed, then the dose escalation is terminated and that dose, or perhaps the previous dose ...

  4. Drug interaction - Wikipedia

    en.wikipedia.org/wiki/Drug_interaction

    A large share of elderly people regularly use five or more medications or supplements, with a significant risk of side-effects from drug–drug interactions. [2] Drug interactions can be of three kinds: additive (the result is what you expect when you add together the effect of each drug taken independently), synergistic (combining the drugs ...

  5. NYT ‘Connections’ Hints and Answers Today, Friday, December 13

    www.aol.com/nyt-connections-hints-answers-today...

    If you've been having trouble with any of the connections or words in Friday's puzzle, you're not alone and these hints should definitely help you out. Plus, I'll reveal the answers further down ...

  6. Why You Shouldn’t Purchase Puppies From Pet Stores This ...

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    Pet purchases and adoptions typically increase around the holidays, with thoughts of adorable puppies or kittens delighting loved ones on Christmas morning.

  7. FOLFOX - Wikipedia

    en.wikipedia.org/wiki/FOLFOX

    The dose schedule given every two weeks is as follows: [5] Day 1–2: Oxaliplatin 100 mg/m 2 IV infusion, given as a 120 minutes IV infusion in 500 mL D5W, concurrent with leucovorin 400 mg/m 2 (or levoleucovorin 200 mg/m 2) IV infusion, followed by 5-FU 400 mg/m 2 IV bolus, followed by 46-hour 5-FU infusion (2400 mg/m 2 for first two cycles, and may be increased to 3000 mg/m 2 if tolerated by ...

  8. How a TikTok Video Led to Arrest of Man Accused of Luring ...

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    Police say a TikTok video post has led to the capture of a Florida man who was on the run for more than three years after he allegedly lured his estranged girlfriend to a cemetery where he killed her.

  9. Oxytetracycline - Wikipedia

    en.wikipedia.org/wiki/Oxytetracycline

    Oxytetracycline, like other tetracyclines, is used to treat many infections, both common and rare.Its better absorption profile makes it preferable to tetracycline for moderately severe acne at a dosage of 250–500 mg four times a day for usually six to eight weeks at a time, but alternatives should be sought if no improvement occurs by three months.

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