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  2. Seroconversion - Wikipedia

    en.wikipedia.org/wiki/Seroconversion

    In immunology, seroconversion is the development of specific antibodies in the blood serum as a result of infection or immunization, ... (HBeAg) is a sign of current ...

  3. HBeAg - Wikipedia

    en.wikipedia.org/wiki/HBeAg

    HBeAg is a hepatitis B viral protein, produced by the HBcAg reading frame. It is an indicator of active viral replication ; this means the person infected with Hepatitis B can likely transmit the virus on to another person (i.e. the person is infectious).

  4. Hepatitis B - Wikipedia

    en.wikipedia.org/wiki/Hepatitis_B

    HBeAg is produced by proteolytic processing of the pre-core protein. In some rare strains of the virus known as hepatitis B virus precore mutants , no HBeAg is present. [ 45 ] The DNA polymerase is encoded by gene P. Gene S is the gene that codes for the surface antigen (HBsAg).

  5. Hepatitis B virus precore mutant - Wikipedia

    en.wikipedia.org/wiki/Hepatitis_B_virus_precore...

    The C gene codes for HBeAg and HBcAg. The C gene has a precore and a core region. If translation is initiated at the precore region, the protein product is HBeAg. If translation begins with the core region, HBcAg is the protein product. HBeAg is a marker of HBV replication and infectivity. The precore region is not necessary for viral replication.

  6. HBcAg - Wikipedia

    en.wikipedia.org/wiki/HBcAg

    HBcAg is an antigen that can be found on the surface of the nucleocapsid core (the inner most layer of the hepatitis B virus).While both HBcAg and HBeAg are made from the same open reading frame, HBcAg is not secreted as a monomer. [3]

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  8. HBsAg - Wikipedia

    en.wikipedia.org/wiki/HBsAg

    Patients who developed antibodies against HBsAg (anti-HBsAg seroconversion) are usually considered non-infectious. HBsAg detection by immunoassay is used in blood screening, to establish a diagnosis of hepatitis B infection in the clinical setting (in combination with other disease markers) and to monitor antiviral treatment.

  9. Window period - Wikipedia

    en.wikipedia.org/wiki/Window_period

    (1) the period that elapses during HBsAg to HBsAb seroconversion, i.e. between the disappearance of surface antigen (HBsAg) from serum and the appearance of HBsAb (anti-HBs), and (2) the period between infection and appearance of HBsAg. During the window of HBsAg to HBsAb seroconversion, IgM anti-core (HBc-IgM) is the only detectable antibody.