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Platelet-rich plasma (PRP), also known as autologous conditioned plasma, is a concentrate of plasma protein derived from whole blood, centrifuged to remove red blood cells but retaining platelets. Though promoted for treating various medical conditions, evidence of its benefits was mixed as of 2020 , showing effectiveness in certain conditions ...
The abnormal protein PrP Sc accumulates in the brain and destroys nerve cells, which leads to the mental and behavioral features of prion diseases. [ citation needed ] Several other changes in the PRNP gene (called polymorphisms) do not cause prion diseases but may affect a person's risk of developing these diseases or alter the course of the ...
Platelet-rich fibrin (PRF) or leukocyte- and platelet-rich fibrin (L-PRF) is a derivative of PRP where autologous platelets and leukocytes are present in a complex fibrin matrix [1] [2] to accelerate the healing of soft and hard tissue [3] and is used as a tissue-engineering scaffold in oral and maxillofacial surgeries.
The regenerative capacity of the mammalian kidney is limited compared to that of lower vertebrates. [citation needed] In the mammalian kidney, the regeneration of the tubular component following an acute injury is well known. Recently regeneration of the glomerulus has also been documented. Following an acute injury, the proximal tubule is ...
Chondrocytes are the cells that make up cartilage and help maintain the extracellular matrix. In osteoarthritis, joint cartilage can become damaged, leading to movement struggles and pain in the ...
Some of the biomedical approaches within the field of regenerative medicine may involve the use of stem cells. [7] Examples include the injection of stem cells or progenitor cells obtained through directed differentiation (cell therapies); the induction of regeneration by biologically active molecules administered alone or as a secretion by ...
Neuroregeneration is the regrowth or repair of nervous tissues, cells or cell products. Neuroregenerative mechanisms may include generation of new neurons , glia , axons , myelin , or synapses . Neuroregeneration differs between the peripheral nervous system (PNS) and the central nervous system (CNS) by the functional mechanisms involved ...
This procedure has been deemed controversial at times, especially when used by athletes.In 2005, the World Anti-Doping Agency ruled that blood-spinning could be used to introduce banned substances, [2] and in 2010 the agency went as far as banning the use of intramuscular injections of PRP in competitive athletes amid some concerns that it boosted performance-enhancing growth factors. [3]
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