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Doxycycline can cause gastrointestinal upset. [70] [71] Oral doxycycline can cause pill esophagitis, particularly when it is swallowed without adequate fluid, or by persons with difficulty swallowing or impaired mobility. [72] Doxycycline is less likely than other antibiotic drugs to cause Clostridioides difficile colitis. [73]
It usually manifests in 1–3 hours after the first dose of antibiotics as fever, chills, rigor, hypotension, headache, tachycardia, hyperventilation, vasodilation with flushing, myalgia (muscle pain), exacerbation of skin lesions and anxiety. The intensity of the reaction indicates the severity of inflammation.
Myalgia or muscle pain is a painful sensation evolving from muscle tissue. It is a symptom of many diseases . The most common cause of acute myalgia is the overuse of a muscle or group of muscles ; another likely cause is viral infection , especially when there has been no injury .
The pain from these contractions can cause mobility limitations and a tense feeling within the muscle, he says. While they’re usually harmless, muscle cramps are undoubtedly uncomfortable.
The duration of the disease can vary from a few weeks to many months or even years. In the first stage of the disease, bacteremia occurs and leads to the classic triad of undulant fevers, sweating (often with a characteristic foul, moldy smell sometimes likened to wet hay), and migratory arthralgia and myalgia (joint and muscle pain). [10]
Delayed onset muscle soreness (DOMS) is the pain and stiffness felt in muscles after unaccustomed or strenuous exercise. The soreness is felt most strongly 24 to 72 hours after the exercise. [1] [2]: 63 It is thought to be caused by eccentric (lengthening) exercise, which causes small-scale damage (microtrauma) to the muscle fibers. After such ...
With an estimated 52.5 million adults in the U.S. affected by arthritis alone and up to 24% of adults experiencing muscle pain during their lifetime, effective topical pain relievers can be life ...
No specific test exists to diagnose polymyalgia rheumatica; many other diseases can cause inflammation and pain in muscles, but a few tests can help narrow down the cause of the pain. Limitation in shoulder motion or swelling of the joints in the wrists or hands, are noted by the doctor. [14]