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Lupus erythematosus is a collection of autoimmune diseases in which the human immune system becomes hyperactive and attacks healthy tissues. [1] Symptoms of these diseases can affect many different body systems, including joints, skin, kidneys, blood cells, heart, and lungs. The most common and most severe form is systemic lupus erythematosus.
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Lupus, formally called systemic lupus erythematosus (SLE), is an autoimmune disease in which the body's immune system mistakenly attacks healthy tissue in many parts of the body. [1] Symptoms vary among people and may be mild to severe. [ 1 ]
Acute cutaneous lupus erythematosus is a cutaneous condition characterized by a bilateral malar rash (also known as a "butterfly rash") and lesions that tend to be transient, and that follow sun exposure. [1] The acute form is distinct from chronic and subacute cutaneous lupus erythematosus, which may have different types of skin lesions. [2]
Although the age at which the disease manifests itself varies as well, most patients are between 30 and 60 years old. [3] The median age was 41 years old in a set of 40 cases, [6] and 42 years old in another Spanish series. [3] Asian patients appear to be affected by lupus erythematosus panniculitis at a slightly younger age group, with a mean ...
[1] [2] Patients observe these symptoms and seek medical advice from healthcare professionals. Because most people are not diagnostically trained or knowledgeable, they typically describe their symptoms in layman's terms, rather than using specific medical terminology. This list is not exhaustive.
The presentation of the disease varies considerably from one patient to another. [8] Generally, the symptoms include nonspecific symptoms common to connective tissue diseases such as fatigue – this is common in autoimmune diseases, and is the patient's primary concern [9] malaise; fever [10] These can be the initial presentation for some ...
While telangiectasia or hypopigmentation may occur, most patients' skin returns to normal. [6] Serologic abnormalities, musculoskeletal complaints, and mild illness are common in patients with SCLE. [7] SCLE typically avoids the face and is more common in sun-exposed areas such as the neck, shoulders, chest, and extensor surfaces of the arms. [6]
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