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  2. Hypothalamic–pituitary–adrenal axis - Wikipedia

    en.wikipedia.org/wiki/Hypothalamicpituitary...

    Schematic of the HPA axis (CRH, corticotropin-releasing hormone; ACTH, adrenocorticotropic hormone) Hypothalamus, pituitary gland, and adrenal cortex The hypothalamicpituitaryadrenal axis (HPA axis or HTPA axis) is a complex set of direct influences and feedback interactions among three components: the hypothalamus (a part of the brain located below the thalamus), the pituitary gland (a ...

  3. Hypothalamic–pituitary hormone - Wikipedia

    en.wikipedia.org/wiki/Hypothalamicpituitary...

    They can be classified as a hypothalamicpituitary axis (HP axis) of which the adrenal (HPA Tooltip hypothalamicpituitaryadrenal axis), gonadal (HPG Tooltip hypothalamicpituitary–gonadal axis), thyroid (HPT Tooltip hypothalamicpituitary–thyroid axis), somatotropic (HPS Tooltip hypothalamicpituitary–somatotropic axis), and ...

  4. Critical illness–related corticosteroid insufficiency - Wikipedia

    en.wikipedia.org/wiki/Critical_illness–related...

    The hypothalamic-pituitary-adrenal axis (HPA axis), in which the hypothalamus and pituitary gland control adrenal secretions, undergoes profound changes during critical illness. Both very high and very low levels of cortisol have been linked to a poor outcome in intensive care patients. [2]

  5. Hypothalamic–pituitary–adrenal axis - en.wikipedia.org

    en.wikipedia.org/api/rest_v1/page/mobile-html...

    The hypothalamicpituitaryadrenal axis (HPA axis or HTPA axis) is a complex set of direct influences and feedback interactions among three components: the hypothalamus (a part of the brain located below the thalamus), the pituitary gland (a pea-shaped structure located below the hypothalamus), and the adrenal (also called "suprarenal ...

  6. Corticotropin-releasing hormone - Wikipedia

    en.wikipedia.org/wiki/Corticotropin-releasing...

    Its main function is the stimulation of the pituitary synthesis of adrenocorticotropic hormone (ACTH), as part of the hypothalamicpituitaryadrenal axis (HPA axis). Corticotropin-releasing hormone (CRH) is a 41-amino acid peptide derived from a 196-amino acid preprohormone.

  7. Corticotropic cell - Wikipedia

    en.wikipedia.org/wiki/Corticotropic_cell

    Corticotropic cells serve an important role within the feedback loop of the hypothalamicpituitaryadrenal (HPA) axis and the stress response. Corticotropes produce and release ACTH, a 39 amino acid peptide hormone, in response to corticotropic releasing hormone (CRH) release from the hypothalamus.

  8. Cortisol awakening response - Wikipedia

    en.wikipedia.org/wiki/Cortisol_awakening_response

    In the hypothalamic-pituitary-adrenal axis the pituitary release of ACTH is regulated by the hypothalamus. This occurs through the hypothalamus's production of the hypophysiotropic hormone corticotropin-releasing hormone , the production of which is subject to circadian influence and the day/night cycle. [ 32 ]

  9. Hans Selye - Wikipedia

    en.wikipedia.org/wiki/Hans_Selye

    The system whereby the body copes with stress, the hypothalamic-pituitary-adrenal axis (HPA axis) system, was also first described by Selye. Selye acknowledged the influence of Claude Bernard (1813–1878), who developed the idea of milieu intérieur, and of the "homeostasis" of Walter Cannon (1871–1945).

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