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  2. Sequence homology - Wikipedia

    en.wikipedia.org/wiki/Sequence_homology

    Top: An ancestral gene duplication produces two paralogs (histone H1.1 and 1.2). A speciation event produces orthologs in the two daughter species (human and chimpanzee). Bottom: in a separate species , a gene has a similar function (histone-like nucleoid-structuring protein) but has a separate evolutionary origin and so is an analog.

  3. HomoloGene - Wikipedia

    en.wikipedia.org/wiki/HomoloGene

    And then it calculates the statistical significance of each match. Cutoffs are made per position and Ks values are set to prevent false "orthologs" from being grouped together. “Paralogs” are identified by finding sequences that are closer within species than other species. This resource ceased making updates in 2014. [2]

  4. Homology (biology) - Wikipedia

    en.wikipedia.org/wiki/Homology_(biology)

    Homology was noticed by Aristotle (c. 350 BC), [1] and was explicitly analysed by Pierre Belon in his 1555 Book of Birds, where he systematically compared the skeletons of birds and humans. The pattern of similarity was interpreted as part of the static great chain of being through the mediaeval and early modern periods: it was not then seen as ...

  5. Cyclin-dependent kinase 1 - Wikipedia

    en.wikipedia.org/wiki/Cyclin-dependent_kinase_1

    Cyclin-dependent kinase 1 also known as CDK1 or cell division cycle protein 2 homolog is a highly conserved protein that functions as a serine/threonine protein kinase, and is a key player in cell cycle regulation. [5]

  6. Period circadian protein homolog 1 - Wikipedia

    en.wikipedia.org/wiki/Period_circadian_protein...

    The PER1 ortholog was first discovered by Ronald Konopka and Seymour Benzer in 1971. During 1997, Period 1 (mPer1) and Period 2 (mPer2) genes were discovered (Sun et al., 1997 and Albretch et al., 1997). Through homology screens with the Drosophila per, these genes were discovered.

  7. EVA1C - Wikipedia

    en.wikipedia.org/wiki/EVA1C

    The paralogs of EVA1C are EVA1A (Eva-1 Homolog A) and EVA1B (Eva-1 Homolog B). [17] [18] The thorny skate (Amblyraja radiata) was found to be the most distant ortholog in EVA1A, EVA1B, and EVA1C. [14] [19] [20] The divergence time of humans and the thorny skate is 464 million years ago. [16]

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    mail.aol.com

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  9. CDC42 - Wikipedia

    en.wikipedia.org/wiki/CDC42

    Cell division control protein 42 homolog (Cdc42 or CDC42) is a protein that in humans is encoded by the CDC42 gene. Cdc42 is involved in regulation of the cell cycle.It was originally identified in S. cerevisiae (yeast) as a mediator of cell division, [5] [6] and is now known to influence a variety of signaling events and cellular processes in a variety of organisms from yeast to mammals.