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Formulations vary from one country to another. Some Preparation H products have phenylephrine, a drug that constricts blood vessels, in a 0.25% concentration, as well as shark liver oil. [4] Another version of Preparation H has hydrocortisone as its only active ingredient in a 1% concentration. [citation needed]
George Speri Sperti (January 17, 1900, Covington, Kentucky – April 29, 1991, Cincinnati, Ohio) was an Italian-American who invented Preparation H hemorrhoid medication. He also invented the Sperti Ultraviolet Lamp, Aspercreme for pain relief, and KVa Power Meter. [1] [2] Sperti graduated from the University of Cincinnati in 1923. Shortly ...
Phenylephrine, sold under the brand names Neosynephrine and Sudafed PE among others, is a medication used as a decongestant for uncomplicated nasal congestion in the form of a nasal spray or oral tablet, [5] to dilate the pupil, to increase blood pressure given intravenously in cases of low blood pressure, and to relieve hemorrhoids as a suppository.
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Pharmaceutical formulation, in pharmaceutics, is the process in which different chemical substances, including the active drug, are combined to produce a final medicinal product. The word formulation is often used in a way that includes dosage form .
[1] [2] [5] [3] [8] Pharmaceutical gels are formed by adding a gelator (gelling agent) to the solvent [5] [6] and active ingredient mixture. Gelators used in gel formulation can be small molecules with low molecular weight or polymers (synthetic, semi-synthetic or natural).
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