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Acetylcholine binds to nicotinic acetylcholine receptors of alpha-motor neurons. [3] The somatic nervous system controls all voluntary muscular systems within the body, and the process of voluntary reflex arcs. [10] The basic route of nerve signals within the efferent somatic nervous system involves a sequence that begins in the upper cell ...
The general (spinal) somatic efferent neurons (GSE, somatomotor, or somatic motor fibers) arise from motor neuron cell bodies in the ventral horns of the gray matter within the spinal cord. They exit the spinal cord through the ventral roots , carrying motor impulses to skeletal muscle through a neuromuscular junction .
A motor neuron (or motoneuron or efferent neuron [1]) is a neuron whose cell body is located in the motor cortex, brainstem or the spinal cord, and whose axon (fiber) projects to the spinal cord or outside of the spinal cord to directly or indirectly control effector organs, mainly muscles and glands. [2]
Upper motor neurons (UMNs) is a term introduced by William Gowers in 1886. They are found in the cerebral cortex and brainstem and carry information down to activate interneurons and lower motor neurons, which in turn directly signal muscles to contract or relax. UMNs represent the major origin point for voluntary somatic movement.
The central nervous system is responsible for the orderly recruitment of motor neurons, beginning with the smallest motor units. [4] Henneman's size principle indicates that motor units are recruited from smallest to largest based on the size of the load. For smaller loads requiring less force, slow twitch, low-force, fatigue-resistant muscle ...
Primary motor cortex is defined anatomically as the region of cortex that contains large neurons known as Betz cells, which, along with other cortical neurons, send long axons down the spinal cord to synapse onto the interneuron circuitry of the spinal cord and also directly onto the alpha motor neurons in the spinal cord which connect to the ...
General depiction of a motor unit, consisting of a motor neuron innervating a group of muscle fibers. Motor unit recruitment is the activation of additional motor units to accomplish an increase in contractile strength in a muscle. [1] A motor unit consists of one motor neuron and all of the muscle fibers it stimulates.
Glutamate released from the upper motor neurons triggers depolarization in the lower motor neurons in the anterior grey column, which in turn causes an action potential to propagate the length of the axon to the neuromuscular junction where acetylcholine is released to carry the signal across the synaptic cleft to the postsynaptic receptors of the muscle cell membrane, signaling the muscle to ...