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  2. Colchicine - Wikipedia

    en.wikipedia.org/wiki/Colchicine

    In July 2009, the FDA approved colchicine as a monotherapy for the treatment of three different indications (familial Mediterranean fever, acute gout flares, and for the prophylaxis of gout flares [66]). This resulted in a 3-year regulatory market exclusivity in the acute and chronic gout indications and a 7-year exclusivity on the FMF indication.

  3. List of drugs known for off-label use - Wikipedia

    en.wikipedia.org/wiki/List_of_drugs_known_for...

    Although the exact mechanism of colchicine is not fully understood, its anti-inflammatory effect for pericarditis appears to be related to its ability to inhibit microtubule self-assembly, resulting in decreased leucocyte motility and phagocytosis. Other non-FDA-approved uses include actinic keratosis, amyloidosis, Peyronie's disease, and ...

  4. List of drugs granted breakthrough therapy designation

    en.wikipedia.org/wiki/List_of_drugs_granted...

    granted for two indications: mast cell leukemia and advanced systemic mastocytosis: Belumosudil: Kadmon Pharmaceuticals: chronic graft-versus-host disease: Pembrolizumab: Merck: high risk, early-stage triple-negative breast cancer: Avalglucosidase alfa: Genzyme: late-onset Pompe disease: Lenvatinib: Eisai Inc

  5. List of therapeutic monoclonal antibodies - Wikipedia

    en.wikipedia.org/wiki/List_of_therapeutic...

    This list of over 500 monoclonal antibodies includes approved and investigational drugs as well as drugs that have been withdrawn from market; consequently, the column Use does not necessarily indicate clinical usage. See the list of FDA-approved therapeutic monoclonal antibodies in the monoclonal antibody therapy page.

  6. How a new FDA-approved drug can — and can’t - AOL

    www.aol.com/fda-approved-drug-t-help-121600044.html

    In early 2023, the U.S. Food and Drug Administration (FDA) granted accelerated approval to a new Alzheimer’s drug called Leqembi. (Biogen, a biotechnology company, and Eisai, a pharmaceutical ...

  7. Food and Drug Administration - Wikipedia

    en.wikipedia.org/wiki/Food_and_Drug_Administration

    The United States Food and Drug Administration (FDA or US FDA) is a federal agency of the Department of Health and Human Services.The FDA is responsible for protecting and promoting public health through the control and supervision of food safety, tobacco products, caffeine products, dietary supplements, prescription and over-the-counter pharmaceutical drugs (medications), vaccines ...

  8. Adobe forecasts fiscal 2025 revenue below estimates on slower ...

    www.aol.com/news/adobe-forecasts-fiscal-2025...

    Adobe expects foreign exchange volatility and the company's shift towards subscriptions to cut into its fiscal 2025 revenue by about $200 million. The company is making significant investments in ...

  9. From a loose emu to surfing dog: Watch the biggest animal ...

    www.aol.com/loose-emu-surfing-dog-watch...

    Whether gearing toward the wholesome, peculiar or straight up terrifying, here are some of the most memorable animal videos of 2024.

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