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D-dimer (or D dimer) is a dimer that is a fibrin degradation product (FDP), a small protein fragment present in the blood after a blood clot is degraded by fibrinolysis. It is so named because it contains two D fragments of the fibrin protein joined by a cross-link , hence forming a protein dimer .
The purpose of the rule is to select the best method of investigation (e.g. D-dimer testing, CT angiography) for ruling in or ruling out the diagnosis of PE, and to improve the interpretation and accuracy of subsequent testing, based on a Bayesian framework for the probability of the diagnosis.
More than half of adult workers in moldy/humid buildings suffer from nasal or sinus symptoms due to mold exposure. [11] Prevention of mold exposure and its ensuing health issues begins with the prevention of mold growth in the first place by avoiding a mold-supporting environment. Extensive flooding and water damage can support extensive mold ...
A D-dimer test can also be used to assist with excluding the diagnosis or to signal a need for further testing. [5] Diagnosis is most commonly confirmed by ultrasound of the suspected veins. [5] VTE becomes much more common with age. The condition is rare in children, but occurs in almost 1% of those ≥ age 85 annually. [3]
Nikki Glaser made history at the 2025 Golden Globes and took full advantage of her moment by poking fun at multiple celebrities in her monologue.
The rationale behind this decision is that further testing (specifically CT angiogram of the chest) may cause more harm (from radiation exposure and contrast dye) than the risk of PE. [50] The PERC rule has a sensitivity of 97.4% and specificity of 21.9% with a false negative rate of 1.0% (16/1666).
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