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Grey matter is distributed at the surface of the cerebral hemispheres (cerebral cortex) and of the cerebellum (cerebellar cortex), as well as in the depths of the cerebrum (the thalamus; hypothalamus; subthalamus, basal ganglia – putamen, globus pallidus and nucleus accumbens; as well as the septal nuclei), cerebellum (deep cerebellar nuclei ...
In humans, the cerebrum is the largest and best-developed of the five major divisions of the brain. The cerebrum is made up of the two cerebral hemispheres and their cerebral cortices (the outer layers of grey matter), and the underlying regions of white matter. [2] Its subcortical structures include the hippocampus, basal ganglia and olfactory ...
The outer part of the cerebrum is the cerebral cortex, made up of grey matter arranged in layers. It is 2 to 4 millimetres (0.079 to 0.157 in) thick, and deeply folded to give a convoluted appearance. [21] Beneath the cortex is the cerebral white matter. The largest part of the cerebral cortex is the neocortex, which has
The pallium is a layer of grey matter that lies on the surface of the forebrain and is the most complex and most recent evolutionary development of the brain as an organ. [44] In reptiles and mammals, it is called the cerebral cortex. Multiple functions involve the pallium, including smell and spatial memory. In mammals, where it becomes so ...
The evolutionary diversifications and specialization in functions of the dorsal pallium have been more difficult to decipher. It is widely believed to be the progenitor of the bulk of the mammalian cerebral cortex, although the evidence for this is considered by some anatomists not yet to be conclusive. [2]
The neocortex is the most developed in its organisation and number of layers, of the cerebral tissues. [5] The neocortex consists of the grey matter, or neuronal cell bodies and unmyelinated fibers, surrounding the deeper white matter (myelinated axons) in the cerebrum. This is a very thin layer though, about 2–4 mm thick. [6]
Cerebral small vessel disease can cause lesions in the white matter and a decrease in gray or white matter volume. Gray matter forms the brain’s outermost layer and is involved in several ...
The periaqueductal gray (PAG), also known as the central gray, is a brain region that plays a critical role in autonomic function, motivated behavior and behavioural responses to threatening stimuli. [1] [2] PAG is also the primary control center for descending pain modulation. It has enkephalin-producing cells that suppress pain.