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DNA base flipping, or nucleotide flipping, is a mechanism in which a single nucleotide base, or nucleobase, is rotated outside the nucleic acid double helix. [1] This occurs when a nucleic acid-processing enzyme needs access to the base to perform work on it, such as its excision for replacement with another base during DNA repair.
In biology, parts of the DNA double helix that need to separate easily, such as the TATAAT Pribnow box in some promoters, tend to have a high AT content, making the strands easier to pull apart. [29] In the laboratory, the strength of this interaction can be measured by finding the melting temperature T m necessary to break half of the hydrogen ...
The most favored conformation occurs when there are high salt concentrations. There are some base substitutions but they require an alternating purine-pyrimidine sequence. The N2-amino of G H-bonds to 5' PO, which explains the slow exchange of protons and the need for the G purine. Z-DNA base pairs are nearly perpendicular to the helix axis.
African elephants are Earth's largest land animals, remarkable mammals that are very intelligent and highly social. Fresh evidence of this comes in a study that documents alarming population ...
A 66-year-old paedophile who sexually abused two girls more than 30 years ago has been jailed for 22 years. Kevin Calderbank carried out the sexual assaults in Peterborough between 1985 and 1989.
You dictate available feed portions, from 0.5-4.5 pounds depending on the size of your flock. The Feedomatic is built to last, made of metal and plastic. See it for yourself at Blain’s Farm and ...
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3579 S High St, Columbus, OH · Directions · (614) 409-0683