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Cobalt is essential to the metabolism of all animals. It is a key constituent of cobalamin, also known as vitamin B 12, the primary biological reservoir of cobalt as an ultratrace element. [1] [2] Bacteria in the stomachs of ruminant animals convert cobalt salts into vitamin B 12, a compound which can only be produced by bacteria or archaea.
Vitamin B 12 is a coordination complex of cobalt, which occupies the center of a corrin ligand and is further bound to a benzimidazole ligand and adenosyl group. [18] Several related species are known and these behave similarly, in particular, all function as vitamins. This collection of compounds is sometimes referred to as "cobalamins".
Co 2+ - cobalt ions are present in the human body in amounts from 1 to 2 mg. [4] Cobalt is observed in the heart, liver, kidney, and spleen, and considerably smaller quantities in the pancreas, brain, and serum. [4] [5] Cobalt is a necessary component of vitamin B 12 and a fundamental coenzyme of cell mitosis. [5]
The five major minerals in the human body are calcium, phosphorus, potassium, sodium, and magnesium. [2] The remaining minerals are called " trace elements ". The generally accepted trace elements are iron , chlorine , cobalt , copper , zinc , manganese , molybdenum , iodine , selenium , [ 5 ] and bromine ; [ 6 ] there is some evidence that ...
Not all elements which are found in the human body in trace quantities play a role in life. Some of these elements are thought to be simple common contaminants without function (examples: caesium, titanium), while many others are thought to be active toxins, depending on amount (cadmium, mercury, lead, radioactives).
Cobalt is also used in the petroleum industry as a catalyst when refining crude oil. This is to purge it of sulfur, which is very polluting when burned and causes acid rain. [11] Cobalt is the active center of a group of coenzymes called cobalamins. Vitamin B 12, the best-known example of the type, is an essential vitamin for all animals.
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Trace metals within the human body include iron, lithium, zinc, copper, chromium, nickel, cobalt, vanadium, molybdenum, manganese and others. [1] [2] [3] Some of the trace metals are needed by living organisms to function properly and are depleted through the expenditure of energy by various metabolic processes of living organisms.