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Aspirin-exacerbated respiratory disease (AERD), also called NSAID-exacerbated respiratory disease (N-ERD) or historically aspirin-induced asthma and Samter's Triad, is a long-term disease defined by three simultaneous symptoms: asthma, chronic rhinosinusitis with nasal polyps, and intolerance of aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs).
Aspirin acts as an acetylating agent where an acetyl group is covalently attached to a serine residue in the active site of the COX enzyme. [1] This makes aspirin different from other NSAIDs (such as diclofenac and ibuprofen), which are reversible inhibitors; aspirin creates an allosteric change in the structure of the COX enzyme. [2]
Treatment Antibiotics, antispasmodics, mesalamine, rifaximin, corticosteroids Diverticular disease is when problems occur due to diverticulosis , a benign condition defined by the formation of pouches (diverticula) from weak spots in the wall of the large intestine . [ 1 ]
An asthma attack can also feel a little like a panic attack in some situations. “But asthma can also cause anxiety, so they can double up on each other,” says Dr. Mustafa.
For women, better diet quality was significantly associated with lower levels of pain, with reductions ranging from 37.2% to 38.8%, and with body fat levels having no influence on this relationship.
Aspirin is also used long-term to help prevent further heart attacks, ischaemic strokes, and blood clots in people at high risk. [10] For pain or fever, effects typically begin within 30 minutes. [10] Aspirin works similarly to other NSAIDs but also suppresses the normal functioning of platelets. [10] One common adverse effect is an upset ...
The Mayo Clinic diet was created by weight management practitioners at the Mayo Clinic and was designed as a lifestyle change program to promote gradual and sustained weight loss, says Melissa ...
Anti-inflammatory or antiphlogistic is the property of a substance or treatment that reduces inflammation or swelling. Anti-inflammatory drugs , also called anti-inflammatories , make up about half of analgesics .
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