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Folic acid is a synthetic derivative of folate and is acquired by dietary supplementation. [25] Multi-vitamin dietary supplements contain folic acid as well as other B vitamins. Non-prescription folic acid is available as a dietary supplement in some countries, and some countries require the fortification of wheat flour, corn meal or rice with ...
One potential issue associated with high doses of folic acid is that it has a masking effect on the diagnosis of pernicious anaemia due to vitamin B 12 deficiency, and may even precipitate or exacerbate neuropathy in vitamin B12-deficient individuals.
Folic acid metabolism and 5-MTHF transport across the choroid plexus epithelium in the brain. Red arrows and red crosses indicate the alternative pathway induced by FRα deficiency. Blue arrows indicate effects of folinic acid treatment.
[59] [60] All individuals who have the ability to become pregnant are advised to get 400 micrograms of folic acid daily. [61] [62] This daily 400 mcg dose of folic acid can be found in most multivitamins advertised as for women. [63] Higher doses can be found in pre-natal multivitamins but those doses may not be necessary for everyone.
The new legislation will require millers to add folic acid to non-wholemeal wheat flour from the end of 2026. Folic acid is a synthetic form of vitamin B9 and is also known as folate.
Nutritional causes are vitamin and mineral deficiencies and non-nutritional causes include infections. The number one cause of this type of anemia, however, is iron deficiency. [12] An insufficient intake of iron, Vitamin B12, and folic acid impairs the bone marrow function. The lack of iron within a person's body can also stem from ulcer bacteria.
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