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Unasyn is the trade name for two related antibiotic drugs: Ampicillin/sulbactam , a fixed-dose combination medication of the penicillin antibiotic combination ampicillin/sulbactam Sultamicillin , an oral form of the penicillin antibiotic combination ampicillin/sulbactam
Sulbactam is a β-lactamase inhibitor. This drug is given in combination with β-lactam antibiotics to inhibit β-lactamase, an enzyme produced by bacteria that destroys the antibiotics. [1] It was patented in 1977 and approved for medical use in 1986. [2]
Ampicillin-sulbactam only comes in a parenteral formulation to be either used as intravenous or intramuscular injections, and can be formulated for intravenous infusion. [2] [17] It is formulated in a 2:1 ratio of ampicillin:sulbactam. The commercial preparations available include: [17] 1.5 grams (1 gram ampicillin and 0.5 gram sulbactam)
Sultamicillin, sold under the brand name Unasyn among others, is an oral form of the penicillin antibiotic combination ampicillin/sulbactam. It is used for the treatment of bacterial infections of the upper and lower respiratory tract , the kidneys and urinary tract , skin and soft tissues , among other organs.
ATC code J01 Antibacterials for systemic use is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed by the World Health Organization (WHO) for the classification of drugs and other medical products.
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