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Lyme disease can be tricky to diagnose, given that the symptoms can mimic those of other illnesses, says Thomas Russo, M.D., professor and chief of infectious disease at the University at Buffalo ...
Lyme disease, also known as Lyme borreliosis, is a tick-borne disease caused by species of Borrelia bacteria, transmitted by blood-feeding ticks in the genus Ixodes. [4] [9] [10] The most common sign of infection is an expanding red rash, known as erythema migrans (EM), which appears at the site of the tick bite about a week afterwards. [1]
Lyme disease symptoms. According to Mayo Clinic, Lyme disease symptoms commonly occur in stages. Common stage 1 symptoms that show up 3 to 30 days after a tick bite include:
Lyme disease is caused by infected black-legged (or deer) ticks and symptoms of the disease may vary, depending on how long it takes to discover the signs. Show comments Advertisement
"Untreated Lyme disease can produce a wide range of symptoms, depending on the stage of infection," read the CDC's Lyme disease symptoms website. "These include fever, rash, facial paralysis, an ...
Afzelius published his work 12 years later and speculated the rash came from the bite of an Ixodes tick, meningitic symptoms and signs in a number of cases and that both sexes were affected. This rash was known as erythema chronicum migrans, the skin rash found in early-stage Lyme disease. [18]
The genomic variations have direct implications on the clinical symptoms of tick-borne Lyme disease. For example, B. burgdorferi s.s.’s tick-borne Lyme disease may manifest with arthritis-like symptoms. [9] In contrast, B. garinii’s tick-borne Lyme disease may cause an infection of the central nervous system. [9]
Eight are known to cause Lyme disease or Borreliosis. [6] The major Borrelia species causing Lyme disease are Borrelia burgdorferi, Borrelia afzelii, and Borrelia garinii. [23] All species that cause Lyme disease are referred to collectively as B. burgdorferi sensu lato, [10] while B. burgdorferi itself is specified as B. burgdorferi sensu stricto.
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