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De Quervain's thyroiditis, also known as subacute granulomatous thyroiditis or giant cell thyroiditis, is a self-limiting inflammatory illness of the thyroid gland. [1] De Quervain thyroiditis is characterized by fever, flu-like symptoms, a painful goiter, and neck pain.
There may be symptoms of thyroid overactivity, such as weight loss, a fast or irregular heart rate, tremor, and perspiration; [1] [2] but such symptoms occur in only half of all cases. [5] The most common type of hyperthyroidism, Graves' disease , may additionally cause eye problems ( Graves' ophthalmopathy ) and skin changes of the legs ...
Subclinical hyperthyroidism is a milder form of hyperthyroidism characterized by low or undetectable serum TSH level, but with a normal serum free thyroxine level. [32] Although the evidence for doing so is not definitive, treatment of elderly persons having subclinical hyperthyroidism could reduce the number of cases of atrial fibrillation. [33]
The diagnosis of subacute thyroiditis can be made clinically by eliciting risk factors, associated symptoms, and physical examination. [ 1 ] [ 2 ] [ 3 ] Further work-up to differentiate between the etiologies of subacute thyroiditis can include: thyroid function tests (TFTs), inflammatory markers , complete blood count (CBC), and thyroid ...
Sub-clinical hyperthyroidism has been reported in 63% of euthyroid Graves' disease, [56] but only in 4% of cases where Graves' disease was in remission. [57] Subclinical hyperthyroidism has an 8% risk of converting to overt hyperthyroidism at 1 year, and a 26% risk at 5 years. [50]
Graves' disease, also known as toxic diffuse goiter or Basedow’s disease, is an autoimmune disease that affects the thyroid. [1] It frequently results in and is the most common cause of hyperthyroidism. [5]
Case studies of patients with diagnosed hyperthyroidism showed that only about half of them complained of symptoms characteristic of TM. [13] Further examination as described above indicated that about 75% of the studied patients showed signs of muscle fiber degeneration. [ 14 ]
Thyroiditis is generally caused by an immune system attack on the thyroid, resulting in inflammation and damage to the thyroid cells. This disease is often considered a malfunction of the immune system and can be associated with IgG4-related systemic disease, in which symptoms of autoimmune pancreatitis, retroperitoneal fibrosis and noninfectious aortitis also occur.