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Penicillin is an antibiotic isolated from growing Penicillium mold in a fermenter. The mold is grown in a liquid culture containing sugar and other nutrients including a source of nitrogen. As the mold grows, it uses up the sugar and starts to make penicillin only after using up most of the nutrients for growth.
The principal commercial strain of Penicillium chrysogenum (the Peoria strain) produces penicillin G as the principal component when corn steep liquor is used as the culture medium. [8] When phenoxyethanol or phenoxyacetic acid are added to the culture medium, the mould produces penicillin V as the main penicillin instead.
Penicillium camemberti, used in the production of Camembert, Brie and Cambozola cheeses; Penicillium candidum, which is used in making Brie and Camembert. It has been reduced to synonymy with Penicillium camemberti; Penicillium chrysogenum (previously known as Penicillium notatum), which produces the antibiotic penicillin; Penicillium claviforme
Penicillium camemberti: fungus: cheese [2] [5] v Penicillium caseifulvum: fungus: cheese [2] Penicillium chrysogenum: fungus: cheese [2] Penicillium chrysogenum: fungus: meat sausage [5] Penicillium commune: fungus: cheese (surface-ripened) [2] [4] Penicillium nalgiovense: fungus: cheese [2] Penicillium nalgiovense: fungus: meat ham ...
"The isopenicillin-N acyltransferase of Penicillium chrysogenum has isopenicillin-N amidohydrolase, 6-aminopenicillanic acid acyltransferase and penicillin amidase activities, all of which are encoded by the single penDE gene". European Journal of Biochemistry. 215 (2): 323–332. doi: 10.1111/j.1432-1033.1993.tb18038.x. ISSN 0014-2956
Almecillin , [1] also known as penicillin O, is a penicillin that is similar in antibiotic action to penicillin G. It is obtained by isolation from Penicillium chrysogenum . [ 2 ]
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[17] From then on, Fleming's mould was synonymously referred to as P. notatum and P. chrysogenum. But Thom adopted and popularised the use of P. chrysogenum. [18] In addition to P. notatum, newly discovered species such as P. meleagrinum and P. cyaneofulvum were recognised as members of P. chrysogenum in 1977. [19]
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