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Lymph node metastasis is the spread of cancer cells into a lymph node.. Lymph node metastasis is different from malignant lymphoma.Lymphoma is a cancer of lymph node, rather than cancer in the lymph node, because lymphoma originates from the lymph node itself, instead of originating elsewhere (e.g., the breast or colon) and spreading to the lymph nodes.
Lymphovascular invasion, especially in carcinomas, usually precedes spread to the lymph nodes that drain the tissue in which the tumour arose. Conversely, cancers with lymph node spread (known as a lymph node metastases), usually have lymphovascular invasion. Lymph node metastases usually precede secondary tumours, i.e. distant metastases.
The concept of sentinel lymph node surgery is to determine if the cancer has spread to the very first draining lymph node (called the "sentinel lymph node") or not. If the sentinel lymph node does not contain cancer, then there is a high likelihood that the cancer has not spread to any other area of the body. [2]
Each woman has a different number of lymph nodes in her body, so determining how many nodes to remove is based on location, rather than number. [4] The lymph nodes serve as a filtering system for the lymphatic system, so it is important to preserve as many as possible, while also ridding the body of all cancer cells.
N: degree of spread to regional lymph nodes. Nx: lymph nodes cannot be assessed; N0: no regional lymph nodes metastasis; N1: regional lymph node metastasis present; at some sites, tumor spread to closest or small number of regional lymph nodes; N2: tumor spread to an extent between N1 and N3 (N2 is not used at all sites)
In the other 20-30%, the breast cancer will return as Stage 4, also known as metastatic, when the cancer has spread to other parts of the body beyond the lymph nodes near the breast.
I’ll have the lymph nodes removed, then six more weeks of radiation after this. I’m staying motivated through this knowing that other people have had cancer—and beat it.
Because they spread slowly, they tend to have fewer signs and symptoms when first diagnosed and may not require immediate treatment. Symptoms can include swollen but painless lymph nodes, unexplained fever, and unintended weight loss. [2] There are several subtypes, the most common of which is follicular lymphoma.
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