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It has a molecular mass of 66.5 kDa. The gene for albumin is located on chromosome 4 in locus 4q13.3 and mutations in this gene can result in anomalous proteins. The human albumin gene is 16,961 nucleotides long from the putative 'cap' site to the first poly(A) addition site. It is split into 15 exons that are symmetrically placed within the 3 ...
The HIV p17 matrix protein (MA) is a 17 kDa protein, of 132 amino acids, which comprises the N-terminus of the Gag polyprotein.It is responsible for targeting Gag polyprotein to the plasma membrane via interaction with PI(4,5)P2 through its highly basic region (HBR). [3]
The average size of a protein increases from Archaea to Bacteria to Eukaryote (283, 311, 438 residues and 31, 34, 49 kDa respectively) due to a bigger number of protein domains constituting proteins in higher organisms. [48] For instance, yeast proteins are on average 466 amino acids long and 53 kDa in mass. [39]
Globulins aren't only a major blood protein, but can also be sex hormone-binding globulin. This type of globulin can transport androgens and estradiol in the blood. There is a specific receptor called SHBG-R that is on the membranes of the sex steroid-responsive cells which shows how it affects androgens and estradiol.
In molecular biology, the mass of macromolecules is referred to as their molecular weight and is expressed in kDa, although the numerical value is often approximate and representative of an average. The terms "molecular mass", "molecular weight", and "molar mass" may be used interchangeably in less formal contexts where unit- and quantity ...
GroEL is a double-ring 14mer with a greasy hydrophobic patch at its opening and can accommodate the native folding of substrates 15-60 kDa in size. GroES (is a single-ring heptamer that binds to GroEL in the presence of ATP or transition state analogues of ATP hydrolysis, such as ADP-AlF 3. It is like a cover that covers GroEL (box/bottle).
The two mouse ROCK isoforms, ROCK1 and ROCK2, have high homology.They have 65% amino acid sequences in common and 92% homology within their kinase domains. [1] [4]ROCKs are homologous to other metazoan kinases such as myotonic dystrophy kinase (), DMPK-related cell division control protein 42 ()-binding kinases (MRCK) and citron kinase.
Cre recombinase is a widely used tool in the field of molecular biology. The enzyme's unique and specific recombination system is exploited to manipulate genes and chromosomes in a huge range of research, such as gene knock out or knock in studies. The enzyme's ability to operate efficiently in a wide range of cellular environments (including ...