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Bone pain affects almost 70% of people with multiple myeloma and is one of the most common symptoms. [2]: 653 [23] Myeloma bone pain usually involves the spine and ribs and worsens with activity. Persistent, localized pain may indicate a pathological bone fracture. Involvement of the vertebrae may lead to spinal cord compression or kyphosis.
The pandemic presents a psychological stressor for pre-existent death anxiety fears. COVID-19 death anxiety was found to influence people's judgement throughout their lives. [83] In an Australian study, those who fear that they are more prone to contracting and dying from COVID-19 have higher levels of death anxiety.
A myoma is a type of tumor that involves muscle cells. [1] There are two main types of myoma: Leiomyomas which occur in smooth muscle. [1] They most commonly occur as uterine fibroids, but may also form in other locations. Rhabdomyomas which occur in striated muscle. [1] [2] [3] They are rare tumors, occur in childhood and often become malignant.
A leiomyoma, also known as a fibroid, is a benign smooth muscle tumor that very rarely becomes cancer (0.1%). They can occur in any organ, but the most common forms occur in the uterus, small bowel, and the esophagus. Polycythemia may occur due to increased erythropoietin production as part of a paraneoplastic syndrome.
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Pain is the most obvious symptom of angioleiomyomas. Wind and cold exposure can set off paroxysmal episodes of pain. It is believed to be caused by smooth muscle contractions that are active and cause localized ischemia. It seems that rest is a relieving aspect. [4]
The most recent COVID-19 vaccine should offer protection against the XEC variant, Russo says. “The most recent version of the vaccine seems to be reasonably well-matched,” he says.