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  2. Chronic lymphocytic leukemia - Wikipedia

    en.wikipedia.org/wiki/Chronic_lymphocytic_leukemia

    Deaths. 60,700 (2015) [7] Chronic lymphocytic leukemia ( CLL) is a type of cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell ). [2] [8] Early on, there are typically no symptoms. [2] Later, non-painful lymph node swelling, feeling tired, fever, night sweats, or weight loss for no clear reason may occur.

  3. Richter's transformation - Wikipedia

    en.wikipedia.org/wiki/Richter's_transformation

    CLL/SLL is the most common adult leukemia in Western countries, accounting for 1.2% of the new cancers diagnosed each year in the United States. It usually occurs in older adults (median age at diagnosis 70) and follows an indolent course over many years. About 1-10% of CLL/SLLs develop a Richter's transformation at a rate of 0.5–1% per year.

  4. Cancer in dogs - Wikipedia

    en.wikipedia.org/wiki/Cancer_in_dogs

    Cancer is the leading cause of death in dogs. [1] It is estimated that 1 in 3 domestic dogs will develop cancer, which is the same incidence of cancer among humans. [2] Dogs can develop a variety of cancers and most are very similar to those found in humans. Dogs can develop carcinomas of epithelial cells and organs, sarcomas of connective ...

  5. Lymphoma in animals - Wikipedia

    en.wikipedia.org/wiki/Lymphoma_in_animals

    Lymphoma in animals. Lymphoma in a Golden Retriever. Lymphoma (lymphosarcoma) in animals is a type of cancer defined by a proliferation of malignant lymphocytes within solid organs such as the lymph nodes, bone marrow, liver and spleen. The disease also may occur in the eye, skin, and gastrointestinal tract .

  6. Acute lymphoblastic leukemia - Wikipedia

    en.wikipedia.org/wiki/Acute_lymphoblastic_leukemia

    Deaths. 111,000 (2015) [10] Acute lymphoblastic leukemia ( ALL) is a cancer of the lymphoid line of blood cells characterized by the development of large numbers of immature lymphocytes. [1] Symptoms may include feeling tired, pale skin color, fever, easy bleeding or bruising, enlarged lymph nodes, or bone pain. [1]

  7. ZAP70 - Wikipedia

    en.wikipedia.org/wiki/ZAP70

    CLL is a cancer that develops from overproduction of B cells in the bone marrow. In people with CLL, higher levels of ZAP-70 confers a worse prognosis; CLL patients that are positive for the marker ZAP-70 have an average survival of 8 years, whereas those that are negative for ZAP-70 have an average survival of more than 25 years.

  8. Indolent lymphoma - Wikipedia

    en.wikipedia.org/wiki/Indolent_lymphoma

    Indolent lymphoma, also known as low-grade lymphoma, is a group of slow-growing non-Hodgkin lymphomas (NHLs). [3] Because they spread slowly, they tend to have fewer signs and symptoms when first diagnosed and may not require immediate treatment. Symptoms can include swollen but painless lymph nodes, unexplained fever, and unintended weight loss.

  9. B-cell prolymphocytic leukemia - Wikipedia

    en.wikipedia.org/wiki/B-cell_prolymphocytic_leukemia

    Hematology, oncology. B-cell prolymphocytic leukemia, referred to as B-PLL, is a rare blood cancer. It is a more aggressive, but still treatable, form of leukemia . Specifically, B-PLL is a prolymphocytic leukemia (PLL) that affects prolymphocytes – immature forms of B-lymphocytes and T-lymphocytes – in the peripheral blood, bone marrow ...