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Tropicamide, sold under the brand name Mydriacyl among others, is a medication used to dilate the pupil and help with examination of the eye. [3] Specifically it is used to help examine the back of the eye. [4] It is applied as eye drops. [3] Effects occur within 40 minutes and last for up to a day. [3]
Medications for glaucoma usually come in the form of medicated eye drops. Prostaglandins (Xalatan, Travatan Z, Vyzulta): These help to relieve pressure by increasing the outflow of your aqueous ...
Mydriasis is frequently induced by drugs for certain ophthalmic examinations and procedures, particularly those requiring visual access to the retina. Fixed, unilateral mydriasis could be a symptom of raised intracranial pressure. The opposite, constriction of the pupil, is referred to as miosis. Both mydriasis and miosis can be physiological.
Afterwards in sunny weather they can cause dazzling and photophobia until the effect of the mydriatic has worn off. In some countries including Russia and Italy, Tropicamide, a mydriatic eye drop, is used to some degree as an inexpensive recreational drug. [7] Like other anticholinergics, when taken recreationally, tropicamide acts as a deliriant.
Because of that, extra caution should be taken when prescribing cyclopentolate to patients who are already taking other anticholinergic drugs. A possible ocular ( eye -related) side effect is increase in pressure inside the eye, which is of particular concern when there is a predisposition toward or a presence of glaucoma .
Glaucoma medication is divided into groups based on chemical structure and pharmacologic action. The goal of currently available glaucoma therapy is to preserve visual function by lowering intraocular pressure (IOP) in patients that have an increased intraocular pressure.
However, its drug form, physostigmine salicylate, has poor bioavailability. [14] Physostigmine also has a miotic function, causing pupillary constriction. It is useful in treating mydriasis. Physostigmine also increases outflow of the aqueous humor in the eye, making it useful in the treatment of glaucoma. [15]
Pilocarpine is in the miotics family of medication. [11] It works by activating cholinergic receptors of the muscarinic type which cause the trabecular meshwork to open and the aqueous humor to drain from the eye. [1] Pilocarpine was isolated in 1874 by Hardy and Gerrard and has been used to treat glaucoma for more than 100 years.
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