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SYNGAP1-related intellectual disability is a monogenetic developmental and epileptic encephalopathy that affects the central nervous system. [ 1 ] [ 2 ] Symptoms include intellectual disability , epilepsy , autism , sensory processing deficits, hypotonia and unstable gait .
Emil Kraepelin in 1923 first outlined a set of symptoms common in people with chronic epilepsy, the most prominent of which is intermittent depressive episodes. [3] These mood changes occur without any external triggers, during the interictal phase (between seizures).
Syndromes are characterized into 4 groups based on epilepsy type: [1] a. Generalized onset epilepsy syndromes. These epilepsy syndromes have only generalized-onset seizures and include both the idiopathic generalized epilepsies (specifically childhood absence epilepsy, juvenile absence epilepsy, juvenile myoclonic epilepsy and epilepsy with generalized tonic- clonic seizures alone), as well as ...
This is an accepted version of this page This is the latest accepted revision, reviewed on 27 January 2025. The following is a list of mental disorders as defined at any point by the Diagnostic and Statistical Manual of Mental Disorders (DSM) or the International Classification of Diseases (ICD). A mental disorder, also known as a mental illness, mental health condition, or psychiatric ...
There are a variety of disabilities affecting cognitive ability.This is a broad concept encompassing various intellectual or cognitive deficits, including intellectual disability (formerly called mental retardation), deficits too mild to properly qualify as intellectual disability, various specific conditions (such as specific learning disability), and problems acquired later in life through ...
The syndrome can be difficult to diagnose and may be misdiagnosed as autism, pervasive developmental disorder, hearing impairment, learning disability, auditory processing disorder, attention deficit hyperactivity disorder (ADHD), intellectual disability, childhood schizophrenia, or emotional/behavioral problems. An EEG (electroencephalogram ...
For example, people with depression have an increased risk for developing new-onset epilepsy. [59] The presence of comorbid depression or anxiety in people with epilepsy is associated with a poorer quality of life, increased mortality, increased healthcare use and a worse response to treatment (including surgical).
Small, medium and large DPBC trials and open small and medium-sized clinical trials demonstrate that new treatments for children with ASD for oxidative stress are associated with improvements in baseline symptoms of ASD, sleep, gastrointestinal symptoms, hyperactivity, seizures and parental impression, sensory and motor symptoms.
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