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  2. Potency (pharmacology) - Wikipedia

    en.wikipedia.org/wiki/Potency_(pharmacology)

    In pharmacology, potency or biological potency [1] is a measure of a drug's biological activity expressed in terms of the dose required to produce a pharmacological effect of given intensity. [2]

  3. EC50 - Wikipedia

    en.wikipedia.org/wiki/EC50

    The term "potency" refers to the EC 50 value. The lower the EC 50 , the less the concentration of a drug is required to produce 50% of maximum effect and the higher the potency. The EC 10 and EC 90 concentrations to induce 10% and 90% maximal responses are defined similarly.

  4. Template:Relative oral potencies of estrogens - Wikipedia

    en.wikipedia.org/wiki/Template:Relative_oral...

    Relative oral potencies of estrogens Estrogen HF Tooltip Hot flashes VE Tooltip Vaginal epithelium UCa Tooltip Urinary calcium FSH Tooltip Follicle-stimulating hormone LH Tooltip Luteinizing hormone

  5. Dose–response relationship - Wikipedia

    en.wikipedia.org/wiki/Dose–response_relationship

    The parameters of the dose response curve reflect measures of potency (such as EC50, IC50, ED50, etc.) and measures of efficacy (such as tissue, cell or population response). A commonly used dose–response curve is the EC 50 curve, the half maximal effective concentration, where the EC 50 point is defined as the inflection point of the curve.

  6. Intrinsic activity - Wikipedia

    en.wikipedia.org/wiki/Intrinsic_activity

    Intrinsic activity (IA) and efficacy refer to the relative ability of a drug-receptor complex to produce a maximum functional response. This must be distinguished from the affinity, which is a measure of the ability of the drug to bind to its molecular target, and the EC 50, which is a measure of the potency of the drug and which is proportional to both efficacy and affinity.

  7. Equianalgesic - Wikipedia

    en.wikipedia.org/wiki/Equianalgesic

    An equianalgesic chart is a conversion chart that lists equivalent doses of analgesics (drugs used to relieve pain). Equianalgesic charts are used for calculation of an equivalent dose (a dose which would offer an equal amount of analgesia) between different analgesics. [1]

  8. Loewe additivity - Wikipedia

    en.wikipedia.org/wiki/Loewe_additivity

    Let and be doses of compounds 1 and 2 producing in combination an effect .We denote by and the doses of compounds 1 and 2 required to produce effect alone (assuming this conditions uniquely define them, i.e. that the individual dose-response functions are bijective).

  9. Effective dose (pharmacology) - Wikipedia

    en.wikipedia.org/wiki/Effective_dose_(pharmacology)

    In pharmacology, an effective dose (ED) or effective concentration (EC) is the dose or concentration of a drug that produces a biological response. [1] [2] The term "effective dose" is used when measurements are taken in vivo, while "effective concentration" is used when the measurements are taken in vitro.

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