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Mucous membrane pemphigoid is a rare chronic autoimmune subepithelial blistering disease characterized by erosive lesions of the mucous membranes and skin. [3] It is one of the pemphigoid diseases that can result in scarring.
It results either from disease (conjunctival sequelae of trachoma) or trauma. Cicatricial pemphigoid [1] and, in severe cases, rosacea may cause symblepharon. Congenital symblepharon may be seen with cryptophthalmos. [2] Its treatment is symblepharectomy.
Pemphigoid is a group of rare autoimmune blistering diseases of the skin and mucous membranes.As its name indicates, pemphigoid is similar in general appearance to pemphigus, [1] however unlike pemphigus, pemphigoid does not feature acantholysis, a loss of connections between skin cells.
Gestational pemphigoid: IgG1: NC16A terminal of BPAG2 BPAG1: 180 230 Cicatricial pemphigoid: C-terminal of BPAG2: 180 Ocular cicatricial pemphigoid: Integrin beta-4 subunit: 200 Antiepiligrin cicatricial pemphigoid [nb 1] Laminin 5 (Epiligrin, Laminin 332) Linear IgA bullous dermatosis: LAD1 portion of BPAG2 Collagen type VII: 97 290/145 ...
There are many diseases known to cause ocular or visual changes. Diabetes , for example, is the leading cause of new cases of blindness in those aged 20–74, with ocular manifestations such as diabetic retinopathy and macular edema affecting up to 80% of those who have had the disease for 15 years or more.
Cicatrising diseases such as Stevens–Johnson syndrome or cicatricial ocular pemphigoid; Inflammatory diseases such as herpes simplex infection or ulcerative blepharitis; Trachoma [11] Cicatricial conjunctivitis [12] Mucous membrane pemphigoid: ocular form of mucous membrane pemphigoid may cause ankyloblepharon (4th stage of foster grading ...
MVD, which is frequently fatal and is related to the much better-known Ebola virus, is sometimes known as "bleeding eye disease" because it damages people's blood vessels, causing them to bleed ...
Ocular trauma [10] Corneal ulceration [10] Xerophthalmia, caused by Vitamin A deficiency [10] Trachoma [11] Onchocerciasis [12] Mucous membrane pemphigoid: Ocular form of mucous membrane pemphigoid may cause corneal opacity and loss of vision. [13]