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A systematic review has found that diabetic peripheral neuropathy affects 30% of diabetes patients. [1] Diabetic neuropathy is implicated in 50–75% of nontraumatic amputations. The main risk factor for diabetic neuropathy is hyperglycemia. In the DCCT (Diabetes Control and Complications Trial, 1995) study, the annual incidence of neuropathy ...
Peripheral neuropathy, often shortened to neuropathy, refers to damage or disease affecting the nerves. [ 1] Damage to nerves may impair sensation, movement, gland function, and/or organ function depending on which nerve fibers are affected. Neuropathies affecting motor, sensory, or autonomic nerve fibers result in different symptoms.
Alcoholic polyneuropathy is a neurological disorder in which peripheral nerves throughout the body malfunction simultaneously. It is defined by axonal degeneration in neurons of both the sensory and motor systems and initially occurs at the distal ends of the longest axons in the body.
Neurology. Proximal diabetic neuropathy, also known as diabetic amyotrophy, is a complication of diabetes mellitus that affects the nerves that supply the thighs, hips, buttocks and/or lower legs. Proximal diabetic neuropathy is a type of diabetic neuropathy characterized by muscle wasting, weakness, pain, or changes in sensation/numbness of ...
Polyneuropathy (from Greek poly- 'many' neuro- 'nerve' and -pathy 'sickness') is damage or disease affecting peripheral nerves ( peripheral neuropathy) in roughly the same areas on both sides of the body, featuring weakness, numbness, and burning pain. [ 1] It usually begins in the hands and feet and may progress to the arms and legs and ...
Frequency. 4.1%-12.4% (12-month prevalence, US adults) [ 1] Neuropathic pain is pain caused by a lesion or disease of the somatosensory nervous system. [ 2][ 3] Neuropathic pain may be associated with abnormal sensations called dysesthesia or pain from normally non-painful stimuli ( allodynia ). It may have continuous and/or episodic ...
Neurology. Small fiber peripheral neuropathy is a type of peripheral neuropathy that occurs from damage to the small unmyelinated and myelinated peripheral nerve fibers. These fibers, categorized as C fibers and small Aδ fibers, are present in skin, peripheral nerves, and organs. [ 1] The role of these nerves is to innervate some skin ...
Any condition resulting in decreased peripheral sensation, proprioception, and fine motor control: Diabetes mellitus neuropathy (the most common in the U.S. today, resulting in destruction of foot and ankle joints), with Charcot joints in 1/600–700 diabetics; related to long-term high blood glucose levels.
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