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Renal corpuscle showing glomerulus and glomerular capillaries Figure 2: (a) Diagram of the juxtaglomerular apparatus: it has specialized cells working as a unit which monitor the sodiujuxtaglomerular apparatus: it has three types of specm content of the fluid in the distal convoluted tubule (not labelled - it is the tubule on the left) and adjust the glomerular filtration rate and the rate of ...
The glomerulus is a small tuft of capillaries containing two cell types. Endothelial cells, which have large fenestrae, are not covered by diaphragms. Mesangial cells are modified smooth muscle cells that lie between the capillaries. They regulate blood flow by their contractile activity and secrete extracellular matrix, prostaglandins, and ...
The juxtaglomerular apparatus consists of three types of cells: the macula densa, in the distal straight tubule (thick ascending limb of the loop of Henle), after which the distal convoluted tubule begins [2] [3] juxtaglomerular cells, (also known as granular cells) which secrete renin; extraglomerular mesangial cells
The kidney has many functions, which a well-functioning kidney realizes by filtering blood in a process known as glomerular filtration. A major measure of kidney function is the glomerular filtration rate (GFR). The glomerular filtration rate is the flow rate of filtered fluid through the kidney.
A higher fluid flow rate in the TAL allows less time for dilution of the tubular fluid so that MD chloride concentration increases. [5] Glomerular flow is decreased if the chloride concentration is above the target value. Constricting the smooth muscle cells in the afferent arteriole, results in a reduced concentration of chloride at the MD.
The first known globular cluster, now called M 22, was discovered in 1665 by Abraham Ihle, a German amateur astronomer. [4] [5] [6] The cluster Omega Centauri, easily visible in the southern sky with the naked eye, was known to ancient astronomers like Ptolemy as a star, but was reclassified as a nebula by Edmond Halley in 1677, [7] then finally as a globular cluster in the early 19th century ...
The carotid body is a small cluster of peripheral chemoreceptor cells and supporting sustentacular cells situated at the bifurcation of each common carotid artery in its tunica externa. [ 1 ] [ 2 ] The carotid body detects changes in the composition of arterial blood flowing through it, mainly the partial pressure of arterial oxygen , but also ...
Hemoglobin is an iron-containing protein that gives red blood cells their color and facilitates transportation of oxygen from the lungs to tissues and carbon dioxide from tissues to the lungs to be exhaled. [3] Red blood cells are the most abundant cell in the blood, accounting for about 40-45% of its volume. Red blood cells are circular ...