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Prolene is a brand of synthetic polypropylene used in monofilament nonabsorbable sutures and meshes. The suture is indicated for skin closure and general soft tissue approximation and ligation. Its advantages include minimal tissue reactivity and durability.
Graft-versus-leukemia (GvL) is a specific type of GvT effect. As the name of this effect indicates, GvL is a reaction against leukemic cells of the host. GvL requires genetic disparity because the effect is dependent on the alloimmunity principle. GvL is a part of the reaction of the graft against the host.
Acute Promyelocytic Leukemia (APL) is a subtype of Acute Myeloid Leukemia, known for its accumulation of abnormal, course, densely granulated promyelocytes in the bone marrow. [6] The excessive proliferation of promyelocytes, attributing at least 30% of the myeloid cells in the bone marrow, result in a depletion of blood cells, including white ...
The bone marrow produces the cellular elements of the blood, including platelets, red blood cells and white blood cells. While much information can be gleaned by testing the blood itself (drawn from a vein by phlebotomy ), it is sometimes necessary to examine the source of the blood cells in the bone marrow to obtain more information on ...
Acute promyelocytic leukemia is characterized by a chromosomal translocation involving the retinoic acid receptor alpha (RARA) gene on chromosome 17. [3] In 95% of cases of APL, the RARA gene on chromosome 17 is involved in a reciprocal translocation with the promyelocytic leukemia gene (PML) on chromosome 15, a translocation denoted as t(15;17)(q22;q21). [3]
These blood cells are not fully developed and are called blasts or leukemia cells. [2] Symptoms may include bleeding and bruising, bone pain, fatigue, fever, and an increased risk of infections. [2] These symptoms occur due to a lack of normal blood cells. [2] Diagnosis is typically made by blood tests or bone marrow biopsy. [2]
Blood is normally sterile. [1] The presence of bacteria in the blood is termed bacteremia, and the presence of fungi is called fungemia. [2] Minor damage to the skin [3] or mucous membranes, which can occur in situations like toothbrushing or defecation, [4] [5] can introduce bacteria into the bloodstream, but this bacteremia is normally transient and is rarely detected in cultures because the ...
Multiple tests for specific blood components, such as a glucose test or a cholesterol test, are often grouped together into one test panel called a blood panel or blood work. Blood tests are often used in health care to determine physiological and biochemical states, such as disease , mineral content, pharmaceutical drug effectiveness, and ...