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Major US medical authorities, including the Infectious Diseases Society of America, [5] the American Academy of Neurology, [6] and the National Institutes of Health, [7] are careful to distinguish the diagnosis and treatment of "patients who have had well-documented Lyme disease and who remain symptomatic for many months to years after ...
Lyme disease, also known as Lyme borreliosis, is a tick-borne disease caused by species of Borrelia bacteria, transmitted by blood-feeding ticks in the genus Ixodes. [4] [9] [10] The most common sign of infection is an expanding red rash, known as erythema migrans (EM), which appears at the site of the tick bite about a week afterwards. [1]
Chronic Lyme disease is distinct from untreated late-stage Lyme disease, which can cause arthritis, peripheral neuropathy and/or encephalomyelitis. Chronic Lyme disease is also distinct from post-treatment Lyme disease syndrome (PTLDS) when symptoms linger after standard antibiotic treatments.
Lyme disease is caused by infected black-legged (or deer) ticks and symptoms of the disease may vary, depending on how long it takes to discover the signs. Show comments Advertisement
Treatment for Lyme disease varies depending on the case and symptoms, but almost always includes a course of oral or intravenous antibiotics, per the CDC. Even with treatment, though, 5% to 10% of ...
Acrodermatitis chronica atrophicans (ACA) is a skin rash indicative of the third or late stage of European Lyme borreliosis. ACA is a dermatological condition that takes a chronically progressive course and finally leads to a widespread atrophy of the skin. Involvement of the peripheral nervous system is often observed, specifically polyneuropathy.
The genomic variations have direct implications on the clinical symptoms of tick-borne Lyme disease. For example, the tick-borne Lyme disease caused by B. burgdorferi s.s. may manifest with arthritis-like symptoms. [9] In contrast, B. garinii’s tick-borne Lyme disease may cause an infection in the central nervous system. [9]
"Erythema migrans is the only manifestation of Lyme disease in the United States that is sufficiently distinctive to allow clinical diagnosis in the absence of laboratory confirmation." [ 8 ] [ 9 ] Often, but not always, mentions of a target lesion (bull's-eye lesion) are talking about erythema migrans.
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