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As a consequence of the biochemical reactions in which homocysteine is involved, deficiencies of vitamin B 6, folic acid (vitamin B 9), and vitamin B 12 can lead to high homocysteine levels. [2] Other possible causes of hyperhomocysteinemia include genetics, excessive methionine intake, and other diseases.
In the body, homocysteine can be recycled into methionine or converted into cysteine with the aid of vitamin B 6, B 9, and B 12. [3] High levels of homocysteine in the blood (hyperhomocysteinemia) is regarded as a marker of cardiovascular disease, likely working through atherogenesis, which can result in ischemic injury.
“Whole-grain toast or cereal provides B vitamins, which may help lower homocysteine and risk for heart disease. Rolled oats are known to lower serum cholesterol as well.”
ADMA's role has been linked with elevated levels of homocysteine. [ 6 ] [ 7 ] [ 8 ] Whilst approaches at modifying the latter with oral supplements of folic acid were strongly suggested, studies have shown this fails to give any clinical benefit and suggested that B vitamins might instead increase some cardiovascular risks.
High blood levels of homocysteine have been linked to Alzheimer’s disease and other forms of dementia. Butternut squash Winter squashes such as butternut squash, acorn squash, and pumpkin are ...
A recent study even found that people who consumed 7 grams (or 1.4 teaspoons) per day of EVOO had a 28% lower risk of dementia-related deaths compared to participants who never or rarely consumed ...
The second pathway (restricted to liver and kidney in most mammals) involves betaine-homocysteine methyltransferase (BHMT) and requires trimethylglycine as a cofactor. During normal physiological conditions, the two pathways contribute equally to removal of homocysteine in the body. [14]
During the height of the pandemic, the loneliness of people all around the world increased. As such, mental health problems increased as well.