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This article provides a list of autoimmune diseases. These conditions, where the body's immune system mistakenly attacks its own cells, affect a range of organs and systems within the body. Each disorder is listed with the primary organ or body part that it affects and the associated autoantibodies that are typically found in people diagnosed ...
Autoimmune diseases represent a vast and diverse category of disorders that, despite their differences, share some common symptomatic threads. [1] These shared symptoms occur as a result of the body's immune system mistakenly attacking its own cells and tissues, causing inflammation and damage.
Autoimmune polyendocrine syndrome type 2, a form of autoimmune polyendocrine syndrome also known as APS-II, or PAS II, is the most common form of the polyglandular failure syndromes. [2] PAS II is defined as the association between autoimmune Addison's disease and either autoimmune thyroid disease , type 1 diabetes , or both. [ 5 ]
This leads to the organ-specific damage typical of autoimmune disease. [19] Molecular mimicry may be particularly relevant to the tolerance breakdown linked to autoimmune neuropathies. The process known as " molecular mimicry " occurs when an infectious organism that shares epitopes from its host's afflicted tissue triggers an immune response ...
[1] Chronic and progressive onset of autonomic symptoms may indicate diabetes, amyloidosis, or Sjogren's syndrome. AAG can be difficult to distinguish from degenerative autonomic disorders such as pure autonomic failure or multiple system atrophy when autonomic symptoms appear gradually. When the time course is unknown, the presence of ...
In 27% to 50% of cases there is an associated malignancy or a predisposing autoimmune disease. [4] [5] [12] Pre-existing autoimmune diseases can include autoimmune lymphoproliferative syndrome (ALPS), combined variable immunodeficiency (CVID), systemic autoimmune disease, or another disorder of immune dysregulation. [13]
Autoimmune GFAP Astrocytopathy is an autoimmune disease in which the immune system of the patient attacks a protein of the nervous system called glial fibrillary acidic protein (GFAP). It was described in 2016 by researchers of the Mayo Clinic in the United States.
Multiple sclerosis is an autoimmune disease where immune cells attack the neurons of the central nervous system and degrade the myelin that protect them. [12] There is no cure for multiple sclerosis, but disease modifying therapies (DMTs) can slow disease progression and reduce the frequency and severity of relapses.