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Keloid prevention. The best way to get rid of keloids is to avoid getting them in the first place, according to Macrene Alexiades, M.D., Ph.D., of Dermatology and Laser Surgery Center of New York ...
Appropriate treatment of a keloid scar is age-dependent: radiotherapy, anti-metabolites and corticosteroids would not be recommended to be used in children, in order to avoid harmful side effects, like growth abnormalities. [14] In adults, corticosteroids combined with 5-FU and PDL in a triple therapy, enhance results and diminish side effects ...
A hypertrophic scar is a cutaneous condition characterized by deposits of excessive amounts of collagen which gives rise to a raised scar, but not to the degree observed with keloids. [1] Like keloids, they form most often at the sites of pimples, body piercings, cuts and burns. They often contain nerves and blood vessels.
The exact mechanism of action of silicone gel sheeting has not been fully studied. Currently, many proposed mechanisms explain the efficacy of such treatment, including the occlusion and hydration effect, increased body surface temperature, polarized electric charge, immunological effects, etc. [9] The occlusion and hydration effect is the most studied mechanism of action.
Lone excision of keloid scars, however, shows a recurrence rate close to 45%. A clinical study is currently ongoing to assess the benefits of a treatment combining surgery and laser-assisted healing in hypertrophic or keloid scars. Subcision is a process used to treat deep rolling scars left behind by acne or other skin diseases.
Formic acid, topical, is a common treatment for plantar warts, which works by being applied over a period of time, causing the body to reject the wart. [ 17 ] Fluorouracil cream, a chemotherapy agent sometimes used to treat skin cancer , can be used on particularly resistant warts, by blocking viral DNA and RNA production and repair.
[17] [18] Therefore, most current textbooks present a classification based on location (for example, conditions of the mucous membrane), morphology (chronic blistering conditions), etiology (skin conditions resulting from physical factors), and so on.
Tranilast (INN, brand name Rizaben) is an antiallergic drug. It was developed by Kissei Pharmaceuticals and was approved in 1982 for use in Japan and South Korea for bronchial asthma . Indications for keloid and hypertrophic scar were added in the 1980s.
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