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  2. Celecoxib - Wikipedia

    en.wikipedia.org/wiki/Celecoxib

    Celecoxib, sold under the brand name Celebrex among others, is a COX-2 inhibitor and nonsteroidal anti-inflammatory drug (NSAID). [7] It is used to treat the pain and inflammation in osteoarthritis , acute pain in adults, rheumatoid arthritis , psoriatic arthritis , ankylosing spondylitis , painful menstruation , and juvenile rheumatoid ...

  3. Cyclooxygenase-2 inhibitor - Wikipedia

    en.wikipedia.org/wiki/Cyclooxygenase-2_inhibitor

    In the CLASS trial which compared Celebrex 800 mg/day to ibuprofen 2400 mg/day and diclofenac 150 mg/day for osteoarthritis or rheumatoid arthritis for six months, Celebrex was associated with significantly fewer upper gastrointestinal complications (0.44% vs. 1.27%, p = 0.04), with no significant difference in incidence of cardiovascular ...

  4. Say Goodbye To Sciatica Pain By Stretching These Two Muscles

    www.aol.com/goodbye-sciatica-pain-stretching-two...

    4. Figure Four Seated Stretch. How to: Sit on a chair with feet flat on ground. Cross right ankle leg over left thigh. Keep spine straight and hinge forward to feel a stretch in glute and hip.

  5. Discovery and development of cyclooxygenase 2 inhibitors

    en.wikipedia.org/wiki/Discovery_and_development...

    [5] [6] It took less than eight years to develop and market the first COX-2 inhibitor, with Celebrex launched in December 1998 and Vioxx launched in May 1999. [ 7 ] [ 8 ] Celecoxib and other COX-2 selective inhibitors, valdecoxib , parecoxib , and mavacoxib , were discovered by a team at the Searle division of Monsanto led by John Talley .

  6. 3 Reasons Pfizer, Inc. Can Overcome Celebrex Patent Loss - AOL

    www.aol.com/news/2014-03-13-3-reasons-pfizer-inc...

    As Celebrex is Pfizer's fourth best-selling drug, raking in $2.9 billion in revenue in 2013 and showing stellar growth year over year of 9%, it's understandable if this court decision rattles ...

  7. FDA approves new type of non-opioid pain medication, 1st of ...

    www.aol.com/fda-approves-type-non-opioid...

    The U.S. Food and Drug Administration (FDA) on Thursday approved a new type of prescription pain medication for adults to treat moderate to severe acute pain. The drug, called Journavx ...

  8. Sciatic nerve - Wikipedia

    en.wikipedia.org/wiki/Sciatic_nerve

    Pain caused by compression or irritation of the sciatic nerve by a problem in the lower back is called sciatica. Common causes of sciatica include the following lower back and hip conditions: spinal disc herniation, degenerative disc disease, lumbar spinal stenosis, spondylolisthesis, and piriformis syndrome. [5]

  9. FDA approves new pain medication as an alternative to ... - AOL

    www.aol.com/news/fda-approves-pain-medication...

    For the first time in two decades, the Food and Drug Administration (FDA) has approved a new class of medication that provides an alternative to addictive opioids for patients looking to manage ...

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