Search results
Results from the WOW.Com Content Network
Chromosome 6 is one of the 23 pairs of chromosomes in humans.People normally have two copies of this chromosome. Chromosome 6 spans nearly 171 million base pairs (the building material of DNA) and represents between 5.5 and 6% of the total DNA in cells.
After Fas stimulation, Daxx is activated and plays its role of pro-apoptotic protein in activating the c-JUN-N-Terminal Kinase pathway. This pathway normally regulates stress-induced cell death. It is also essential for development of nerval system by programmed cell death. The real apoptotic process starts after activating this pathway.
Additional experimentation identified CRSP3 as the exact gene responsible for KISS1 regulation within chromosome 6. In clinical evidence studies, KISS1 and Kisspeptin were found in primary metastatic tumors, and growing tumors showing decreased levels of KISS1 and Kisspeptin. [16] In conclusion, kisspeptin plays a large role in tumor suppression.
Chemokine receptor 6 also known as CCR6 is a CC chemokine receptor protein which in humans is encoded by the CCR6 gene. [5] CCR6 has also recently been designated CD196 (cluster of differentiation 196). The gene is located on the long arm of Chromosome 6 (6q27) on the Watson (plus) strand.
[5] [6] MAP3K5 gene coding for the protein is located on chromosome 6 at locus 6q22.33. [7] and the transcribed protein contains 1,374 amino acids with 11 kinase subdomains. [citation needed] Northern blot analysis shows that MAP3K5 transcript is abundant in human heart and pancreas. [8]
In the human genome, STAT6 protein is encoded by the STAT6 gene, located on the chromosome 12q13.3-q14.1. [6] The gene encompasses over 19 kb and consists of 23 exons . [ 7 ] STAT6 shares structural similarity with the other STAT proteins and is composed of the N-terminal domain , DNA binding domain , SH3- like domain, SH2 domain and ...
IRF4 is a transcription factor belonging to the Interferon Regulatory Factor (IRF) family of transcription factors. [8] [9] In contrast to some other IRF family members, IRF4 expression is not initiated by interferons; rather, IRF4 expression is promoted by a variety of bioactive stimuli, including antigen receptor engagement, lipopolysaccharide (LPS), IL-4, and CD40.
Tyrosine-protein phosphatase non-receptor type 6, also known as Src homology region 2 domain-containing phosphatase-1 (SHP-1), is an enzyme that in humans is encoded by the PTPN6 gene. [ 5 ] Function