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MALT (mucosa-assisted lymphoid tissue) lymphoma is a rare form of non-Hodgkin lymphoma. It’s also called extranodal marginal zone lymphoma. It develops in the lining of your belly (gastric MALT), but may also appear in your lungs, skin, thyroid, salivary gland or near your eye (non-gastric MALT).
Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue, or MALT lymphoma, is a slow-growing type of non-Hodgkin lymphoma that develops in the lymphoid tissue outside the lymph nodes. MALT lymphoma is the most common form of marginal zone lymphoma, though it’s still rare.
MALT lymphoma (also called MALToma) is a form of lymphoma involving the mucosa-associated lymphoid tissue (MALT), frequently of the stomach, but virtually any mucosal site can be affected. It is a cancer originating from B cells in the marginal zone of the MALT.
MALT lymphoma is a slow growing lymphoma, usually diagnosed in the stomach (gastric MALT). But they can also develop in the lung, thyroid, salivary glands, eye, skin or soft tissues (non gastric MALT).
Mucosa-associated lymphoid tissue (MALT) lymphoma is an uncommon form of non-Hodgkin lymphoma (NHL). Unlike most lymphomas that begin growing within lymph nodes, this type of lymphoma typically arises from tissue that is present in the lining of certain other organs of the body.
Gastric MALT lymphomas are strongly associated with Helicobacter pylori infection. This pathogen is the most common infectious agent related to worldwide cancers (5.5% of total cancers) [10].
There is limited understanding of the extent to which mucosa-associated lymphoid tissue (MALT) lymphoma affects a patient’s risk of death and how classically considered prognostic factors affect lymphoma-specific vs other noncancer mortality.
MALT lymphoma is a rare B-cell non-Hodgkin's lymphoma that typically runs an indolent or slow-growing clinical course.
MALT lymphomas is defined as an 'extranodal lymphoma composed of morphologically heterogenous small B cells, including marginal zone cells, cells resembling monocytoid cells, small lymphocytes, and scattered immunoblasts and centroblast-like cells'.
Mucosa-associated lymphoid tissue (MALT) lymphoma is categorized as indolent or low-grade B-cell lymphoma; however, high-grade histologic transformation can occur. Median age at presentation is approximately 60 years.