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Acral lentiginous melanoma (ALM) is a rare subtype of melanoma arising on the palms, soles, or under the nails. It is also known as acral melanoma. In early stages, ALM often appears as a dark brown or black macule with variegated colour, and can be nodular and ulcerated in advanced cases.
Acral lentiginous melanoma is a rare skin cancer that’s not caused by exposure to UV rays. We went to dermatologist Kelly Nelson, M.D., and melanoma specialist Isabella C. Glitza Oliva, M.D., Ph.D., to learn more.
Acral lentiginous melanoma is a subtype of cutaneous malignant melanoma. It is comprised of malignant melanocytes, which can become invasive with time. It is often diagnosed at a later stage than the other forms of cutaneous malignant melanoma and in populations that are at a low risk for UV-induced melanomas, which highlights the need for ...
Acral lentiginous melanoma (ALM) is a type of malignant melanoma. Malignant melanoma is a form of skin cancer that happens when the skin cells called melanocytes become cancerous.
Acral lentiginous melanoma is a result of malignant melanocytes at the membrane of the skin (outer layers). [2][3] The pathogenesis of ALM remains unclear, however injury or mechanical stress might play a role in its development. [17][18] Unlike cutaneous melanoma, it is not caused by sunlight or UV radiation. [10] Diagnosis.
Acral lentiginous melanoma (ALM) is the rarest of the four major subtypes of cutaneous melanoma, accounting for 2-3% of all melanomas (1 – 3). ALM occurs predominantly in non-hair-bearing skin of the distal extremities, such as the palms of the hands, soles of the feet, and nailbeds (1, 3 – 6).
Acral lentiginous melanoma is a rare type of skin cancer. It begins when the melanocytes in the skin grow out of control and form tumors. Melanocytes are the cells responsible for making melanin, the pigment that determines the color of the skin. The main sign of acral lentiginous melanoma is a black or brown discoloration that appears on the ...