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Ankylosing spondylitis (AS) is a type of arthritis from the disease spectrum of axial spondyloarthritis. [5] It is characterized by long-term inflammation of the joints of the spine, typically where the spine joins the pelvis. [2] With AS, eye and bowel problems—as well as back pain—may occur. [2]
Ankylosing spondylitis has been linked with dactylitis. It is distinguished by tenosynovitis that affects the flexor tendons resulting in inflammatory swelling in one or more fingers or toes. One of the main indicators that the disease is progressing toward generalized ankylosis is the restriction of cervical spine mobility.
HLA-B27 is a polymorphic form of the HLA-B molecule found in up to 95% of people with ankylosing spondylitis of European ancestry, [16] [17] 70% with reactive arthritis, [18] 60% with psoriatic spondylitis, [12] 25% with peripheral psoriatic arthritis, [17] and 70% with spondylitis associated with inflammatory bowel disease.
Ankylosing spondylitis is a genetic disease with identifiable marks, tends to start showing signs in adolescence or young adulthood, is more likely to affect the lumbar spine, and affects organs. DISH has no indication of a genetic link, is primarily thoracic and does not affect organs other than the lungs, and only indirectly due to the fusion ...
[10] Axial spondyloarthritis can be divided into two classes: Non-radiographic axial spondyloarthritis (nr-axSpA): This term encompasses both the early disease stage of ankylosing spondylitis, in which no radiographic changes are visible yet, as well as less severe forms of ankylosing spondylitis. Radiographic axial spondyloarthritis:
They publish WebMD the Magazine, a patient-directed publication distributed bimonthly free of charge to 85 percent of physician waiting rooms. [13] Medscape is a professional portal for physicians and has training materials, a drug database, and clinical information on 30 medical specialty areas and more than 30 physician discussion boards. [ 14 ]
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Spondylitis is an inflammation of the vertebrae. It is a form of spondylopathy . In many cases, spondylitis involves one or more vertebral joints , as well, which itself is called spondylarthritis .