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  2. Viagra: What It Treats & Its Side Effects ( Plus What It Was ...

    www.aol.com/viagra-treats-side-effects-plus...

    A single tablet of sildenafil can do that — typically, one dose is all that’s required to produce a firmer, longer-lasting hardness. Studies have shown a 70 to 80 percent success rate in ...

  3. Sildenafil - Wikipedia

    en.wikipedia.org/wiki/Sildenafil

    Sildenafil, sold under the brand name Viagra among others, is a medication used to treat erectile dysfunction and pulmonary arterial hypertension. [4] [8] It is also sometimes used off-label for the treatment of certain symptoms in secondary Raynaud's phenomenon. [9] It is unclear if it is effective for treating sexual dysfunction in females. [8]

  4. Is Sildenafil Safe for This Common Male Problem? - AOL

    www.aol.com/sildenafil-safe-common-male-problem...

    Sildenafil is most commonly prescribed to be taken one time per day in doses between 25 and 100 mg for ED. Your healthcare provider will determine the best dosage for you based on a number of factors.

  5. PDE5 inhibitor - Wikipedia

    en.wikipedia.org/wiki/PDE5_inhibitor

    Chemical structure of sildenafil (Viagra), the prototypical PDE5 inhibitor. A phosphodiesterase type 5 inhibitor (PDE5 inhibitor) is a vasodilating drug that works by blocking the degradative action of cGMP-specific phosphodiesterase type 5 (PDE5) on cyclic GMP in the smooth muscle cells lining the blood vessels supplying various tissues.

  6. Discovery and development of phosphodiesterase 5 inhibitors

    en.wikipedia.org/wiki/Discovery_and_development...

    Sildenafil has been shown to be at least as effective as calcium channel blockers in treating severe Raynaud's phenomenon (RP) associated with systemic sclerosis and digital ulceration. [3] When given sildenafil for 4 weeks subjects had reduced mean frequency and duration of Raynaud attacks and a significantly lowered mean Raynaud's condition ...

  7. How to Take Viagra for Best Results - AOL

    www.aol.com/viagra-best-results-105700318.html

    When to Take Viagra: 30-60 Minutes Before Intimacy, Not Earlier. If you’re planning to have intimacy, it’s best to take your recommended dose of Viagra ahead of time.

  8. How Much Viagra Is Too Much? - AOL

    www.aol.com/much-viagra-too-much-105700581.html

    A typical starting dose of Viagra or sildenafil dosage is 50 milligrams. Whether you use sildenafil or Viagra, take a 100-milligram sildenafil dose or a 20-milligram sildenafil dose, the effects ...

  9. Alpha blocker - Wikipedia

    en.wikipedia.org/wiki/Alpha_blocker

    Alpha blockers can treat a small range of diseases such as hypertension, Raynaud's disease, benign prostatic hyperplasia (BPH) and erectile dysfunction. [2] Generally speaking, these treatments function by binding an α-blocker to α receptors in the arteries and smooth muscle.