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Active transport. In cellular biology, active transport is the movement of molecules or ions across a cell membrane from a region of lower concentration to a region of higher concentration —against the concentration gradient. Active transport requires cellular energy to achieve this movement. There are two types of active transport: primary ...
In contrast, paracellular transport is the transfer of substances across an epithelium by passing through an intercellular space between the cells. 1. It differs from transcellular transport, where the substances travel through the cell passing through both the apical membrane and basolateral membrane. 2. Renal physiology.
Cotransporters are capable of moving solutes either up or down gradients at rates of 1000 to 100000 molecules per second. They may act as channels or transporters, depending on conditions under which they are assayed. The movement occurs by binding to two molecules or ions at a time and using the gradient of one solute's concentration to force ...
The transport of glucose across the proximal tubule cell membrane involves a complex process of secondary active transport (also known as co-transport). [3] This process begins with the Na + /K + ATPase on the basolateral membrane. This enzyme uses ATP to pump 3 sodium ions out of the cell into the blood while bringing 2 potassium ions into the ...
Where the hydrolysis of the energy provider is indirect as is the case in secondary active transport, use is made of the energy stored in an electrochemical gradient. For example, in co-transport use is made of the gradients of certain solutes to transport a target compound against its gradient, causing the dissipation of the solute gradient ...
Loop of Henle. In the kidney, the loop of Henle (English: / ˈhɛnli /) (or Henle's loop, Henle loop, [1] nephron loop[2] or its Latin counterpart ansa nephroni) is the portion of a nephron that leads from the proximal convoluted tubule to the distal convoluted tubule. Named after its discoverer, the German anatomist Friedrich Gustav Jakob ...
A membrane transport protein is a membrane protein involved in the movement of ions, small molecules, and macromolecules, such as another protein, across a biological membrane. Transport proteins are integral transmembrane proteins; that is they exist permanently within and span the membrane across which they transport substances.
Solute carrier family. The solute carrier (SLC) group of membrane transport proteins include over 400 members organized into 66 families. [1][2] Most members of the SLC group are located in the cell membrane. The SLC gene nomenclature system was originally proposed by the HUGO Gene Nomenclature Committee (HGNC) and is the basis for the official ...