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Noonan syndrome with multiple lentigines ( NSML) which is part of a group called Ras / MAPK pathway syndromes, [2] is a rare autosomal dominant, [3] multisystem disease caused by a mutation in the protein tyrosine phosphatase, non-receptor type 11 gene ( PTPN11 ). The disease is a complex of features, mostly involving the skin, skeletal and ...
Mongolian spot is a congenital developmental condition—that is, one existing from birth—exclusively involving the skin. The blue colour is caused by melanocytes, melanin -containing cells, that are usually located in the surface of the skin (the epidermis ), but are in the deeper region (the dermis) in the location of the spot. [ 6]
Hyperpigmentation can be diffuse or focal, affecting such areas as the face and the back of the hands. Melanin is produced by melanocytes at the lower layer of the epidermis. Melanin is a class of pigment responsible for producing color in the body in places such as the eyes, skin, and hair. The process of melanin synthesis (melanogenesis ...
Postinflammatory hyperpigmentation ( PIH) is a skin condition characterized by the darkening of the skin ( hyperpigmentation) following an inflammatory injury, such as acne, dermatitis, infectious disease, or trauma. Less frequently, it may occur as a complication of a medical procedure performed on the skin.
Specialty. Dermatology, hematology. Purpura ( / ˈpɜːrpjʊərə / [ 1]) is a condition of red or purple discolored spots on the skin that do not blanch on applying pressure. The spots are caused by bleeding underneath the skin secondary to platelet disorders, vascular disorders, coagulation disorders, or other causes. [ 2]
The skin weighs an average of four kilograms, covers an area of two square metres, and is made of three distinct layers: the epidermis, dermis, and subcutaneous tissue. [1] The two main types of human skin are: glabrous skin, the hairless skin on the palms and soles (also referred to as the "palmoplantar" surfaces), and hair-bearing skin. [3]
Atopic dermatitis. Atopic dermatitis ( AD ), also known as atopic eczema, is a long-term type of inflammation of the skin ( dermatitis ). [ 2] It results in itchy, red, swollen, and cracked skin. [ 2] Clear fluid may come from the affected areas, which can thicken over time. [ 2]
Rodent mite dermatitis. Rodent mite dermatitis (also known as rat mite dermatitis) is an often unrecognized ectoparasitosis occurring after human contact with haematophagous mesostigmatid mites that infest rodents, such as house mice, [ 1] rats [ 2] and hamsters. [ 3] The condition is associated with the tropical rat mite ( Ornithonyssus bacoti ...