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Hyperpigmentation can be diffuse or focal, affecting such areas as the face and the back of the hands. Melanin is produced by melanocytes at the lower layer of the epidermis. Melanin is a class of pigment responsible for producing color in the body in places such as the eyes, skin, and hair. The process of melanin synthesis (melanogenesis ...
Noonan syndrome with multiple lentigines ( NSML) which is part of a group called Ras / MAPK pathway syndromes, [2] is a rare autosomal dominant, [3] multisystem disease caused by a mutation in the protein tyrosine phosphatase, non-receptor type 11 gene ( PTPN11 ). The disease is a complex of features, mostly involving the skin, skeletal and ...
Mongolian spot is a congenital developmental condition—that is, one existing from birth—exclusively involving the skin. The blue colour is caused by melanocytes, melanin -containing cells, that are usually located in the surface of the skin (the epidermis ), but are in the deeper region (the dermis) in the location of the spot. [ 6]
Melasma. Melasma (also known as chloasma faciei, [ 1]: 854 or the mask of pregnancy[ 2] when present in pregnant women) is a tan or dark skin discoloration. Melasma is thought to be caused by sun exposure, genetic predisposition, hormone changes, and skin irritation. [ 3]
Postinflammatory hyperpigmentation ( PIH) is a skin condition characterized by the darkening of the skin ( hyperpigmentation) following an inflammatory injury, such as acne, dermatitis, infectious disease, or trauma. Less frequently, it may occur as a complication of a medical procedure performed on the skin.
Tinea cruris, also known as jock itch, is a common type of contagious, superficial fungal infection of the groin and buttocks region, which occurs predominantly but not exclusively in men and in hot-humid climates. [ 3][ 4] Typically, over the upper inner thighs, there is an intensely itchy red raised rash with a scaly well-defined curved ...
Keratosis pilaris. Keratosis pilaris ( KP; also follicular keratosis, lichen pilaris, or colloquially chicken skin[ 1]) is a common, autosomal - dominant, genetic condition of the skin's hair follicles characterized by the appearance of possibly itchy, small, gooseflesh -like bumps, with varying degrees of reddening or inflammation. [ 2]
The skin weighs an average of four kilograms, covers an area of two square metres, and is made of three distinct layers: the epidermis, dermis, and subcutaneous tissue. [1] The two main types of human skin are: glabrous skin, the hairless skin on the palms and soles (also referred to as the "palmoplantar" surfaces), and hair-bearing skin. [3]
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