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Lovastatin, a compound isolated from Aspergillus terreus, was the first statin to be marketed. Statins (or HMG-CoA reductase inhibitors) are a class of medications that reduce illness and mortality in people who are at high risk of cardiovascular disease. They are the most commonly prescribed cholesterol-lowering drugs.
The top 5 best selling pharmaceuticals 2015–2019. Sales in billion USD. ... Cholesterol: Oct-2002: 2017-Oct 31: ... Takeda Pharmaceuticals North America, Inc:
[111] [114] By 2003, Lipitor had become the best selling pharmaceutical in the United States. [107] From 1996 to 2012, under the trade name Lipitor, atorvastatin became the world's best-selling medication of all time, with more than $125 billion in sales over approximately 14.5 years.
Rosuvastatin. Rosuvastatin, sold under the brand name Crestor among others, is a statin medication, used to prevent cardiovascular disease in those at high risk and treat abnormal lipids. [ 6] It is recommended to be used together with dietary changes, exercise, and weight loss. [ 6] It is taken orally (by mouth).
For normal cholesterol levels, bempedoic acid lowers LDL, or ‘bad’ cholesterol, for people who have side effects from statins, new research finds.
Researchers further estimated that the statin recommendations for U.S. adults would drop from 45.4 million to 28.3 million with a change from PCEs to PREVENT equations. They also noted that many ...
An alternative to statins may help reduce deaths from heart disease among people with high levels of LDL, or “bad” cholesterol, new research finds. When taken as a daily pill, bempedoic acid ...
Hence, in cases where there is too much uncertainty, they are excluded from the list. Having sold more than 600 million copies worldwide,[ 13] Harry Potter by J. K. Rowling is the best-selling book series in history. The first novel in the series, Harry Potter and the Philosopher's Stone, has sold in excess of 120 million copies, [ 14] making ...