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Statins are effective in decreasing mortality in people with pre-existing cardiovascular disease. [34] Pre-existing disease can have many manifestations. Defining illnesses include a prior heart attack, stroke, stable or unstable angina, aortic aneurysm, or other arterial ischemic disease, in the presence of atherosclerosis. [21]
Atherosclerosis. Atherosclerosis[ a] is a pattern of the disease arteriosclerosis, [ 8] characterized by development of abnormalities called lesions in walls of arteries. This is a chronic inflammatory disease involving many different cell types, and driven by elevated levels of cholesterol in the blood. [ 9]
Atorvastatin is a statin medication used to prevent cardiovascular disease in those at high risk and to treat abnormal lipid levels. [ 4] For the prevention of cardiovascular disease, statins are a first-line treatment. [ 4] It is taken by mouth.
Statins reduce cardiovascular death risk in older adults. According to the Centers For Disease Control and Prevention (CDC), heart disease is the leading cause of death for people 65 years and ...
Atherosclerosis is a condition wherein plaque builds up inside arteries, slowly narrowing them and interrupting blood flow. PCE calculations are the current standard, but they are based on decades ...
Elevated cholesterol—specifically high levels of LDL—is the main driver of plaque build-up in blood vessels, which is called atherosclerosis, says Dr. Keith Ferdinand, a cardiologist and ...
The discovery of HMG-CoA (3-hydroxy-3-methylglutaryl-CoA) reductase inhibitors, called statins, was a breakthrough in the prevention of hypercholesterolemia and related diseases. Hypercholesterolemia is considered to be one of the major risk factors for atherosclerosis which often leads to cardiovascular, cerebrovascular and peripheral vascular ...
Arteriosclerosis, literally meaning "hardening of the arteries", is an umbrella term for a vascular disorder characterized by abnormal thickening, hardening, and loss of elasticity [3] of the walls of arteries; [4] this process gradually restricts the blood flow to one's organs and tissues and can lead to severe health risks brought on by atherosclerosis, which is a specific form of ...
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