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sn-Glycerol 3-phosphate [a] [b] is the organic ion with the formula HOCH 2 CH(OH)CH 2 OPO 3 2-. It is one of two stereoisomers of the ester of dibasic phosphoric acid (HOPO 3 2- ) and glycerol . It is a component of bacterial and eukaryotic glycerophospholipids . [ 2 ]
The glycerol also enters the bloodstream and is absorbed by the liver or kidney where it is converted to glycerol 3-phosphate by the enzyme glycerol kinase. Hepatic glycerol 3-phosphate is converted mostly into dihydroxyacetonephosphate (DHAP) and then glyceraldehyde 3-phosphate (GA3P) to rejoin the glycolysis and gluconeogenesis pathway. [15]
Thus, the two substrates of this enzyme are sn-glycerol 3-phosphate and D-glucose, whereas its two products are glycerol and D-glucose 6-phosphate. This enzyme belongs to the family of transferases , specifically those transferring phosphorus-containing groups ( phosphotransferases ) with an alcohol group as acceptor.
Triglycerides are built from three fatty acids, esterified onto each of three hydroxy groups of glycerol, which is derived from glycerol 3-phosphate.In mammals, glycerol 3-phosphate is usually synthesized through glycolysis, a metabolic pathway that degrades glucose into fructose 1,6-bisphosphate and then into two molecules of dihydroxyacetone phosphate, which beget glycerol 3-phosphate and ...
The 3 substrates of this enzyme are ATP, H 2 O, and glycerol-3-phosphate, whereas its 3 products are ADP, phosphate, and glycerol-3-phosphate. This enzyme belongs to the family of hydrolases , specifically those acting on acid anhydrides to catalyse transmembrane movement of substances.
In enzymology, a glucosylglycerol-phosphate synthase (EC 2.4.1.213) is an enzyme that catalyzes the chemical reaction ADP-glucose + sn-glycerol 3-phosphate ⇌ {\displaystyle \rightleftharpoons } 2-(beta-D-glucosyl)-sn-glycerol 3-phosphate + ADP
In enzymology, a glycerol-3-phosphate cytidylyltransferase (EC 2.7.7.39) is an enzyme that catalyzes the chemical reaction. CTP + sn-glycerol 3-phosphate diphosphate + CDP-glycerol. Thus, the two substrates of this enzyme are CTP and sn-glycerol 3-phosphate, whereas its two products are diphosphate and CDP-glycerol.
Glycerol-3-phosphate dehydrogenase (GPDH) is an enzyme that catalyzes the reversible redox conversion of dihydroxyacetone phosphate (a.k.a. glycerone phosphate, outdated) to sn-glycerol 3-phosphate. [2] Glycerol-3-phosphate dehydrogenase serves as a major link between carbohydrate metabolism and lipid metabolism.