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Twin anemia-polycythemia sequence (TAPS) is a chronic type of unbalanced fetal transfusion in monochorionic twins that results in polycythemia in the TAPS recipient and anemia in the TAPS donor due to tiny placental anastomoses. [1] Post-laser TAPS and spontaneous TAPS are the two forms of TAPS.
Twin anemia–polycythemia sequence: Treatment: Fetoscopy and laser ablation; serial amniocentesis: Prognosis: 0–20% survival of one or all fetuses without treatment; [1] 66–85% survival of at least one fetus with treatment, with 6–15% risk of cerebral palsy: Frequency: Around 5–15% of identical twin pregnancies [2]
Treatment for polycythemia varies, and typically involves treating its underlying cause. [6] Treatment of primary polycythemia (see polycythemia vera) could involve phlebotomy, antiplatelet therapy to reduce risk of blood clots, and additional cytoreductive therapy to reduce the number of red blood cells produced in the bone marrow. [7]
Oxytocin treatment for postpartum depression; P. Pelvic girdle pain; Peripartum cardiomyopathy; ... Twin anemia-polycythemia sequence; Twin reversed arterial perfusion;
Twin-twin transfusion syndrome (TTTS) in pregnancies in which twins share a single placenta (hydrops affects the recipient twin) Twin anemia-polycythemia sequence (TAPS) Twin reversed arterial perfusion sequence (TRAPS) Maternal hyperthyroidism; Fetal cardiac defects and skeletal defects; Noonan syndrome
In oncology, polycythemia vera (PV) is an uncommon myeloproliferative neoplasm in which the bone marrow makes too many red blood cells. [1] The majority of cases [ 2 ] are caused by mutations in the JAK2 gene, most commonly resulting in a single amino acid change in its protein product from valine to phenylalanine at position 617.
Aplastic anemia; Acquired pure red cell aplasia; Myeloproliferative disorders. Polycythemia vera; Essential thrombocytosis; Myelofibrosis; Metabolic disorders Amyloidoses. Amyloid light chain (AL) amyloidosis; Environmentally-induced diseases Radiation poisoning; Viral diseases HTLV; HIV [1] Autoimmune diseases Multiple sclerosis [2]
Treatment is done to address the underlying cause. To tide over immediate crisis blood transfusion with packed red blood cells (PRBC) or platelet transfusion may be done. Sometimes there are obvious clinical clues to suggest underlying B12 deficiency for a cause of pancytopenia. [ 6 ]
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