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Pegylated interferon alfa-2b is a drug used to treat melanoma, as an adjuvant therapy to surgery. [3] Also used to treat hepatitis C (typically, in combination with ribavarin), it is no longer recommended due to poor efficacy and adverse side-effects. [4]
Taking this one stage further, the clue word can hint at the word or words to be abbreviated rather than giving the word itself. For example: "About" for C or CA (for "circa"), or RE. "Say" for EG, used to mean "for example". More obscure clue words of this variety include: "Model" for T, referring to the Model T.
Smaller words may be easier to fit in the grid, but longer words give more clues to connecting words. [ 10 ] Care must be given to marking out words that are not explicitly placed in the grid; this occurs when one fills in a vertical sequence of horizontal words, or vice versa.
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Clues and answers must always match in part of speech, tense, aspect, number, and degree. A plural clue always indicates a plural answer and a clue in the past tense always has an answer in the past tense. A clue containing a comparative or superlative always has an answer in the same degree (e.g., [Most difficult] for TOUGHEST). [6]
Leonard Dawe, Telegraph crossword compiler, created these puzzles at his home in Leatherhead. Dawe was headmaster of Strand School, which had been evacuated to Effingham, Surrey. Adjacent to the school was a large camp of US and Canadian troops preparing for D-Day, and as security around the camp was lax, there was unrestricted contact between ...
People showing signs of psychomotor agitation may be experiencing mental tension and anxiety, which comes out physically as: fast or repetitive movements; movements that have no purpose; movements that are not intentional; These activities are the subconscious mind's way of trying to relieve tension [citation needed]. Often people experiencing ...
Pegylated interferon alfa-2a, sold under the brand name Pegasys among others, is medication used to treat hepatitis C and hepatitis B. [3] For hepatitis C it is typically used together with ribavirin and cure rates are between 24 and 92%.